Anti-HSP70 protein monoclonal antibody as well as preparation method and application thereof
The invention relates to a monoclonal antibody capable of recognizing a human HSP70 antigen, a preparation method of the monoclonal antibody and application of the monoclonal antibody in immunodetection. The invention provides an anti-HSP70 protein rabbit monoclonal antibody. An amino acid sequence...
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| creator | LIN YANG JIANG NINGCHENG ZHAO PU LI TING |
| description | The invention relates to a monoclonal antibody capable of recognizing a human HSP70 antigen, a preparation method of the monoclonal antibody and application of the monoclonal antibody in immunodetection. The invention provides an anti-HSP70 protein rabbit monoclonal antibody. An amino acid sequence of a heavy chain variable region of the monoclonal antibody is an amino acid sequence as shown in SEQ ID NO.1; the amino acid sequence of the light chain variable region of the monoclonal antibody is as shown in SEQ ID NO. 2. The antibody has high specificity and sensitivity, can specifically recognize cells expressing HSP70 protein, and is suitable for immunological detection, especially immunohistochemical detection.
本发明涉及一种可以识别人HSP70抗原的单克隆抗体，其制备方法以及其在免疫检测中的用途。本发明提供一种抗HSP70蛋白兔单克隆抗体，所述单克隆抗体的重链可变区的氨基酸序列为SEQ ID NO.1所示的氨基酸序列；所述单克隆抗体轻链可变区的氨基酸序列为SEQ ID NO.2所示的氨基酸序列。该抗体具有高特异性、敏感性，可以特异性识别表达HSP70蛋白的细胞，适用于免疫学检测，特别是免疫组化检测。 |
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本发明涉及一种可以识别人HSP70抗原的单克隆抗体，其制备方法以及其在免疫检测中的用途。本发明提供一种抗HSP70蛋白兔单克隆抗体，所述单克隆抗体的重链可变区的氨基酸序列为SEQ ID NO.1所示的氨基酸序列；所述单克隆抗体轻链可变区的氨基酸序列为SEQ ID NO.2所示的氨基酸序列。该抗体具有高特异性、敏感性，可以特异性识别表达HSP70蛋白的细胞，适用于免疫学检测，特别是免疫组化检测。</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240223&DB=EPODOC&CC=CN&NR=117586392A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25546,76297</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240223&DB=EPODOC&CC=CN&NR=117586392A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIN YANG</creatorcontrib><creatorcontrib>JIANG NINGCHENG</creatorcontrib><creatorcontrib>ZHAO PU</creatorcontrib><creatorcontrib>LI TING</creatorcontrib><title>Anti-HSP70 protein monoclonal antibody as well as preparation method and application thereof</title><description>The invention relates to a monoclonal antibody capable of recognizing a human HSP70 antigen, a preparation method of the monoclonal antibody and application of the monoclonal antibody in immunodetection. The invention provides an anti-HSP70 protein rabbit monoclonal antibody. An amino acid sequence of a heavy chain variable region of the monoclonal antibody is an amino acid sequence as shown in SEQ ID NO.1; the amino acid sequence of the light chain variable region of the monoclonal antibody is as shown in SEQ ID NO. 2. The antibody has high specificity and sensitivity, can specifically recognize cells expressing HSP70 protein, and is suitable for immunological detection, especially immunohistochemical detection.
本发明涉及一种可以识别人HSP70抗原的单克隆抗体，其制备方法以及其在免疫检测中的用途。本发明提供一种抗HSP70蛋白兔单克隆抗体，所述单克隆抗体的重链可变区的氨基酸序列为SEQ ID NO.1所示的氨基酸序列；所述单克隆抗体轻链可变区的氨基酸序列为SEQ ID NO.2所示的氨基酸序列。该抗体具有高特异性、敏感性，可以特异性识别表达HSP70蛋白的细胞，适用于免疫学检测，特别是免疫组化检测。</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNikEKwjAQRbtxIeod4gEK1qLVZSlKVyLoUihjOqWBMTMkA-LtjegBXHwe_Pem2a326vL2cq5WRgIrOm8e7NkSeyADyd65fxmI5olEH0pAgQDqOKWoI_cpSxMhZ7-3jhiQh3k2GYAiLn6cZcvj4dq0OQp3GAUsetSuORVFtdlty_26Lv9p3l9wO4U</recordid><startdate>20240223</startdate><enddate>20240223</enddate><creator>LIN YANG</creator><creator>JIANG NINGCHENG</creator><creator>ZHAO PU</creator><creator>LI TING</creator><scope>EVB</scope></search><sort><creationdate>20240223</creationdate><title>Anti-HSP70 protein monoclonal antibody as well as preparation method and application thereof</title><author>LIN YANG ; JIANG NINGCHENG ; ZHAO PU ; LI TING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN117586392A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>LIN YANG</creatorcontrib><creatorcontrib>JIANG NINGCHENG</creatorcontrib><creatorcontrib>ZHAO PU</creatorcontrib><creatorcontrib>LI TING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIN YANG</au><au>JIANG NINGCHENG</au><au>ZHAO PU</au><au>LI TING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Anti-HSP70 protein monoclonal antibody as well as preparation method and application thereof</title><date>2024-02-23</date><risdate>2024</risdate><abstract>The invention relates to a monoclonal antibody capable of recognizing a human HSP70 antigen, a preparation method of the monoclonal antibody and application of the monoclonal antibody in immunodetection. The invention provides an anti-HSP70 protein rabbit monoclonal antibody. An amino acid sequence of a heavy chain variable region of the monoclonal antibody is an amino acid sequence as shown in SEQ ID NO.1; the amino acid sequence of the light chain variable region of the monoclonal antibody is as shown in SEQ ID NO. 2. The antibody has high specificity and sensitivity, can specifically recognize cells expressing HSP70 protein, and is suitable for immunological detection, especially immunohistochemical detection.
本发明涉及一种可以识别人HSP70抗原的单克隆抗体，其制备方法以及其在免疫检测中的用途。本发明提供一种抗HSP70蛋白兔单克隆抗体，所述单克隆抗体的重链可变区的氨基酸序列为SEQ ID NO.1所示的氨基酸序列；所述单克隆抗体轻链可变区的氨基酸序列为SEQ ID NO.2所示的氨基酸序列。该抗体具有高特异性、敏感性，可以特异性识别表达HSP70蛋白的细胞，适用于免疫学检测，特别是免疫组化检测。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE |
| title | Anti-HSP70 protein monoclonal antibody as well as preparation method and application thereof |
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