Application of Th40 cell subset in preparation of kit for auxiliary diagnosis and evaluation of systemic lupus erythematosus disease activity

The invention discloses application of Th40 cell subpopulation detection in preparation of a kit for auxiliary diagnosis and evaluation of SLE disease activity. The invention is based on the research results that the inventor finds that the expression of the Th40 cell subpopulation in SLE patients with disease activity is obviously increased for the first time, and the higher the disease activity is, the higher the proportion of the Th40 cell subpopulation is. Therefore, the Th40 cell subset can be used as one of laboratory immune related detection indexes for auxiliary diagnosis of SLE, and meanwhile, important reference data is provided for evaluating the disease activity of an SLE patient. 本发明公开了检测Th40细胞亚群在制备辅助诊断和评估SLE疾病活动试剂盒中的应用。本发明是基于发明人首次发现Th40细胞亚群在疾病活动的SLE患者中表达明显升高，且疾病活动度越高Th40细胞亚群占比越高得到的研究成果。从而，Th40细胞亚群可以作为辅助诊断SLE的实验室免疫相关检测指标之一，同时，也为评估SLE患者疾病活动度提供重要的参考资料。