Benzamide derivative for preventing or treating cancer, method for preparing same, and pharmaceutical composition containing same as active ingredient
The present invention relates to a benzamide derivative for preventing or treating cancer, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient. The benzamide derivative provided in one aspect of the present invention can be used for preventin...
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| creator | BYUN YE-JI KANG SEOCK-YONG YUN DAE-SEOK KIM HYE-JUNG JEONG SEUNG-HEE PARK SOH-MI CHO HYE IM KIM DONG-KYU CHOI SUNG-IL LEE KWANG-HO LEE SEUNGUL PARK JI-YEON |
| description | The present invention relates to a benzamide derivative for preventing or treating cancer, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient. The benzamide derivative provided in one aspect of the present invention can be used for preventing or treating cancer by inhibiting EGFR mutation, and can be effectively used as an anticancer agent because it exhibits a significant synergistic effect when administered together with an EGFR antagonist such as cetuximab.
本发明涉及一种用于预防或治疗癌症的苯甲酰胺衍生物、其制备方法和含有其作为活性成分的药物组合物。本发明一方面提供的苯甲酰胺衍生物可通过抑制EGFR突变用于预防或治疗癌症，并且可有效地用作抗癌剂，因为当与EGFR拮抗剂如西妥昔单抗共同给药时，其表现出显著的协同作用。 |
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本发明涉及一种用于预防或治疗癌症的苯甲酰胺衍生物、其制备方法和含有其作为活性成分的药物组合物。本发明一方面提供的苯甲酰胺衍生物可通过抑制EGFR突变用于预防或治疗癌症，并且可有效地用作抗癌剂，因为当与EGFR拮抗剂如西妥昔单抗共同给药时，其表现出显著的协同作用。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240112&DB=EPODOC&CC=CN&NR=117396463A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240112&DB=EPODOC&CC=CN&NR=117396463A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BYUN YE-JI</creatorcontrib><creatorcontrib>KANG SEOCK-YONG</creatorcontrib><creatorcontrib>YUN DAE-SEOK</creatorcontrib><creatorcontrib>KIM HYE-JUNG</creatorcontrib><creatorcontrib>JEONG SEUNG-HEE</creatorcontrib><creatorcontrib>PARK SOH-MI</creatorcontrib><creatorcontrib>CHO HYE IM</creatorcontrib><creatorcontrib>KIM DONG-KYU</creatorcontrib><creatorcontrib>CHOI SUNG-IL</creatorcontrib><creatorcontrib>LEE KWANG-HO</creatorcontrib><creatorcontrib>LEE SEUNGUL</creatorcontrib><creatorcontrib>PARK JI-YEON</creatorcontrib><title>Benzamide derivative for preventing or treating cancer, method for preparing same, and pharmaceutical composition containing same as active ingredient</title><description>The present invention relates to a benzamide derivative for preventing or treating cancer, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient. The benzamide derivative provided in one aspect of the present invention can be used for preventing or treating cancer by inhibiting EGFR mutation, and can be effectively used as an anticancer agent because it exhibits a significant synergistic effect when administered together with an EGFR antagonist such as cetuximab.
本发明涉及一种用于预防或治疗癌症的苯甲酰胺衍生物、其制备方法和含有其作为活性成分的药物组合物。本发明一方面提供的苯甲酰胺衍生物可通过抑制EGFR突变用于预防或治疗癌症，并且可有效地用作抗癌剂，因为当与EGFR拮抗剂如西妥昔单抗共同给药时，其表现出显著的协同作用。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjT0OwjAMhbswIOAOZi9DVQRihArExMReWYmhlhonSkwHDsJ5CYjuTO_Hn_ymxetA8kTHlsBS5AGVB4KbjxAiDSTKcoecNBJ-vUExFEtwpJ23Ixkwfo4JHZWAYiF0GB0aeigb7MF4F3xiZS_ZiyLLyAMmQPOdzVUky3l1Xkxu2Cda_HRWLE_Ha3NeUfAtpZA_C2nbXKpqW-826029r_9h3gxvUkQ</recordid><startdate>20240112</startdate><enddate>20240112</enddate><creator>BYUN YE-JI</creator><creator>KANG SEOCK-YONG</creator><creator>YUN DAE-SEOK</creator><creator>KIM HYE-JUNG</creator><creator>JEONG SEUNG-HEE</creator><creator>PARK SOH-MI</creator><creator>CHO HYE IM</creator><creator>KIM DONG-KYU</creator><creator>CHOI SUNG-IL</creator><creator>LEE KWANG-HO</creator><creator>LEE SEUNGUL</creator><creator>PARK JI-YEON</creator><scope>EVB</scope></search><sort><creationdate>20240112</creationdate><title>Benzamide derivative for preventing or treating cancer, method for preparing same, and pharmaceutical composition containing same as active ingredient</title><author>BYUN YE-JI ; KANG SEOCK-YONG ; YUN DAE-SEOK ; KIM HYE-JUNG ; JEONG SEUNG-HEE ; PARK SOH-MI ; CHO HYE IM ; KIM DONG-KYU ; CHOI SUNG-IL ; LEE KWANG-HO ; LEE SEUNGUL ; PARK JI-YEON</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN117396463A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>BYUN YE-JI</creatorcontrib><creatorcontrib>KANG SEOCK-YONG</creatorcontrib><creatorcontrib>YUN DAE-SEOK</creatorcontrib><creatorcontrib>KIM HYE-JUNG</creatorcontrib><creatorcontrib>JEONG SEUNG-HEE</creatorcontrib><creatorcontrib>PARK SOH-MI</creatorcontrib><creatorcontrib>CHO HYE IM</creatorcontrib><creatorcontrib>KIM DONG-KYU</creatorcontrib><creatorcontrib>CHOI SUNG-IL</creatorcontrib><creatorcontrib>LEE KWANG-HO</creatorcontrib><creatorcontrib>LEE SEUNGUL</creatorcontrib><creatorcontrib>PARK JI-YEON</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BYUN YE-JI</au><au>KANG SEOCK-YONG</au><au>YUN DAE-SEOK</au><au>KIM HYE-JUNG</au><au>JEONG SEUNG-HEE</au><au>PARK SOH-MI</au><au>CHO HYE IM</au><au>KIM DONG-KYU</au><au>CHOI SUNG-IL</au><au>LEE KWANG-HO</au><au>LEE SEUNGUL</au><au>PARK JI-YEON</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Benzamide derivative for preventing or treating cancer, method for preparing same, and pharmaceutical composition containing same as active ingredient</title><date>2024-01-12</date><risdate>2024</risdate><abstract>The present invention relates to a benzamide derivative for preventing or treating cancer, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient. The benzamide derivative provided in one aspect of the present invention can be used for preventing or treating cancer by inhibiting EGFR mutation, and can be effectively used as an anticancer agent because it exhibits a significant synergistic effect when administered together with an EGFR antagonist such as cetuximab.
本发明涉及一种用于预防或治疗癌症的苯甲酰胺衍生物、其制备方法和含有其作为活性成分的药物组合物。本发明一方面提供的苯甲酰胺衍生物可通过抑制EGFR突变用于预防或治疗癌症，并且可有效地用作抗癌剂，因为当与EGFR拮抗剂如西妥昔单抗共同给药时，其表现出显著的协同作用。</abstract><oa>free_for_read</oa></addata></record> |
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| title | Benzamide derivative for preventing or treating cancer, method for preparing same, and pharmaceutical composition containing same as active ingredient |
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