Use of melvidalin and other D1 positive allosteric modulators in treatment of hallucination and dementia-related psychosis
The present invention relates to methods of treatment and dosing regimens for the treatment of hallucination and/or psychosis using Mevidaline, also described as 2-(2, 6-dichlorophenyl)-1-[(1S, 3R)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3, 4-dihydroisoquinolin-2 (1H)-yl] ethanone, an...
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| creator | SVENSSON KARL ANDERS INGEMAR BIGLAND KRISTIN M |
| description | The present invention relates to methods of treatment and dosing regimens for the treatment of hallucination and/or psychosis using Mevidaline, also described as 2-(2, 6-dichlorophenyl)-1-[(1S, 3R)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3, 4-dihydroisoquinolin-2 (1H)-yl] ethanone, and/or pharmaceutical compositions thereof, in particular for the treatment of hallucination and/or psychosis. The hallucination and/or psychosis includes dementia-associated psychosis.
本发明涉及使用美维达林，也描述为2-(2,6-二氯苯基)-1-[(1S,3R)-3-(羟甲基)-5-(3-羟基-3-甲基丁基)-1-甲基-3,4-二氢异喹啉-2(1H)-基]乙酮和/或其药物组合物来治疗幻觉和/或精神病的治疗方法和给药方案，该幻觉和/或精神病包括痴呆相关的精神病。 |
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本发明涉及使用美维达林，也描述为2-(2,6-二氯苯基)-1-[(1S,3R)-3-(羟甲基)-5-(3-羟基-3-甲基丁基)-1-甲基-3,4-二氢异喹啉-2(1H)-基]乙酮和/或其药物组合物来治疗幻觉和/或精神病的治疗方法和给药方案，该幻觉和/或精神病包括痴呆相关的精神病。</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240109&DB=EPODOC&CC=CN&NR=117377470A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240109&DB=EPODOC&CC=CN&NR=117377470A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SVENSSON KARL ANDERS INGEMAR</creatorcontrib><creatorcontrib>BIGLAND KRISTIN M</creatorcontrib><title>Use of melvidalin and other D1 positive allosteric modulators in treatment of hallucination and dementia-related psychosis</title><description>The present invention relates to methods of treatment and dosing regimens for the treatment of hallucination and/or psychosis using Mevidaline, also described as 2-(2, 6-dichlorophenyl)-1-[(1S, 3R)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3, 4-dihydroisoquinolin-2 (1H)-yl] ethanone, and/or pharmaceutical compositions thereof, in particular for the treatment of hallucination and/or psychosis. The hallucination and/or psychosis includes dementia-associated psychosis.
本发明涉及使用美维达林，也描述为2-(2,6-二氯苯基)-1-[(1S,3R)-3-(羟甲基)-5-(3-羟基-3-甲基丁基)-1-甲基-3,4-二氢异喹啉-2(1H)-基]乙酮和/或其药物组合物来治疗幻觉和/或精神病的治疗方法和给药方案，该幻觉和/或精神病包括痴呆相关的精神病。</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDEKwkAQRdNYiHqH8QABQ4TUEhUrK63DsDshA5vdZWcS0NO7QQ9g9Yv_3lsX76cQhB5GcjNbdOwBvYWgAyU4VxCDsPJMgM4FUUpsYAx2cqghCWRcE6GO5HXJDBmbDHtUDt-SpeVjLBNlhyxEeZkhV2VbrHp0Qrvfbor99fJobyXF0JFENORJu_ZeVU3dNMfmcKr_YT5twkeD</recordid><startdate>20240109</startdate><enddate>20240109</enddate><creator>SVENSSON KARL ANDERS INGEMAR</creator><creator>BIGLAND KRISTIN M</creator><scope>EVB</scope></search><sort><creationdate>20240109</creationdate><title>Use of melvidalin and other D1 positive allosteric modulators in treatment of hallucination and dementia-related psychosis</title><author>SVENSSON KARL ANDERS INGEMAR ; BIGLAND KRISTIN M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN117377470A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SVENSSON KARL ANDERS INGEMAR</creatorcontrib><creatorcontrib>BIGLAND KRISTIN M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SVENSSON KARL ANDERS INGEMAR</au><au>BIGLAND KRISTIN M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Use of melvidalin and other D1 positive allosteric modulators in treatment of hallucination and dementia-related psychosis</title><date>2024-01-09</date><risdate>2024</risdate><abstract>The present invention relates to methods of treatment and dosing regimens for the treatment of hallucination and/or psychosis using Mevidaline, also described as 2-(2, 6-dichlorophenyl)-1-[(1S, 3R)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3, 4-dihydroisoquinolin-2 (1H)-yl] ethanone, and/or pharmaceutical compositions thereof, in particular for the treatment of hallucination and/or psychosis. The hallucination and/or psychosis includes dementia-associated psychosis.
本发明涉及使用美维达林，也描述为2-(2,6-二氯苯基)-1-[(1S,3R)-3-(羟甲基)-5-(3-羟基-3-甲基丁基)-1-甲基-3,4-二氢异喹啉-2(1H)-基]乙酮和/或其药物组合物来治疗幻觉和/或精神病的治疗方法和给药方案，该幻觉和/或精神病包括痴呆相关的精神病。</abstract><oa>free_for_read</oa></addata></record> |
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| title | Use of melvidalin and other D1 positive allosteric modulators in treatment of hallucination and dementia-related psychosis |
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