Application of agilawood essential oil in preparation of medicine for relieving inflammation

The invention provides application of agilawood essential oil in preparation of a medicine for relieving inflammation, and belongs to the technical field of medicine biological activity. The agilawood essential oil is prepared through a supercritical carbon dioxide extraction method, and within the concentration range of 1-50 micrograms/mL, the agilawood essential oil can inhibit lipopolysaccharide-induced macrophage active oxygen generation and TNF-alpha, IL-6 and IL-1beta excessive secretion, and inhibit phosphorylation of P65 protein and I kappa B-alpha protein in macrophages, so that the agilawood essential oil can inhibit lipopolysaccharide-induced TNF-alpha, IL-6 and IL-1beta excessive secretion of TNF-alpha, IL-6 and IL-1beta excessive secretion of TNF-alpha, IL-6 and IL-1beta. And an NF-kappa B signal channel is regulated, so that inflammation is relieved. 本发明提出了一种沉香精油在制备缓解炎症药物中的应用，属于药物生物活性技术领域。本发明的沉香精油通过超临界二氧化碳萃取法制备得到，在浓度范围为1～50μg/mL内，沉香精油可以通过抑制脂多糖诱导的巨噬细胞活性氧的产生以及TNF-α、IL-6和IL-1β过度分泌，并通过抑制巨噬细胞中P65蛋白和I