Fish maw oligopeptide and application of fish maw oligopeptide to treatment of fatty liver diseases
The invention discloses a fish maw oligopeptide and application thereof in treating fatty liver diseases, belongs to the technical field of biology, and is used for solving the problems that a peptide fragment has antioxidant activity and fat accumulation of hepatocytes is reduced, an amino acid seq...
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| creator | GE SIQI GAO WEI LIU WAN ZHANG YANSHENG WANG ZUZHE YUAN YANNA |
| description | The invention discloses a fish maw oligopeptide and application thereof in treating fatty liver diseases, belongs to the technical field of biology, and is used for solving the problems that a peptide fragment has antioxidant activity and fat accumulation of hepatocytes is reduced, an amino acid sequence of the fish maw oligopeptide comprises Tyr-Cys-Tyr-Cys-Pro-Arg, and a drug delivery system composed of the fish maw oligopeptide, galactosylated and modified bacterial cellulose and astaxanthin can be used for preparing the fish maw oligopeptide. The liver targeting property and delivery rate are extremely high, accumulation and peroxidation of liver cell lipid can be relieved, and alcoholic or non-alcoholic fatty liver injury can be improved.
一种花胶低聚肽及用于治疗脂肪肝疾病的应用，属于生物技术领域，用于解决肽段具有抗氧化活性，减少肝细胞的脂肪堆积问题，花胶低聚肽氨基酸序列包括Tyr-Cys-Tyr-Cys-Pro-Arg，其与半乳糖基化修饰的细菌纤维素、虾青素组成的给药体系，具有极高的肝靶向性及递送率，能够缓解肝细胞脂质的堆积与过氧化，改善酒精性或非酒精性脂肪性肝损伤。 |
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一种花胶低聚肽及用于治疗脂肪肝疾病的应用，属于生物技术领域，用于解决肽段具有抗氧化活性，减少肝细胞的脂肪堆积问题，花胶低聚肽氨基酸序列包括Tyr-Cys-Tyr-Cys-Pro-Arg，其与半乳糖基化修饰的细菌纤维素、虾青素组成的给药体系，具有极高的肝靶向性及递送率，能够缓解肝细胞脂质的堆积与过氧化，改善酒精性或非酒精性脂肪性肝损伤。</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>DERIVATIVES THEREOF</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>PEPTIDES</subject><subject>POLYSACCHARIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKAjEMANAuDqL-Q_wAh1JBVznucHJyP0KbaqDXhktQ_HtBHB2c3vKWLg6sd5jwCa3wrQmJcSLAmgBFCkc0bhVahvwzWgObCW2iap-FZi8o_KAZEiuhkq7dImNR2nxdue3QX7vzjqSNpIKRKtnYXbw_hH3w4XgK_5w3oV8-kw</recordid><startdate>20240105</startdate><enddate>20240105</enddate><creator>GE SIQI</creator><creator>GAO WEI</creator><creator>LIU WAN</creator><creator>ZHANG YANSHENG</creator><creator>WANG ZUZHE</creator><creator>YUAN YANNA</creator><scope>EVB</scope></search><sort><creationdate>20240105</creationdate><title>Fish maw oligopeptide and application of fish maw oligopeptide to treatment of fatty liver diseases</title><author>GE SIQI ; GAO WEI ; LIU WAN ; ZHANG YANSHENG ; WANG ZUZHE ; YUAN YANNA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN117343138A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>DERIVATIVES THEREOF</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>PEPTIDES</topic><topic>POLYSACCHARIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>GE SIQI</creatorcontrib><creatorcontrib>GAO WEI</creatorcontrib><creatorcontrib>LIU WAN</creatorcontrib><creatorcontrib>ZHANG YANSHENG</creatorcontrib><creatorcontrib>WANG ZUZHE</creatorcontrib><creatorcontrib>YUAN YANNA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GE SIQI</au><au>GAO WEI</au><au>LIU WAN</au><au>ZHANG YANSHENG</au><au>WANG ZUZHE</au><au>YUAN YANNA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Fish maw oligopeptide and application of fish maw oligopeptide to treatment of fatty liver diseases</title><date>2024-01-05</date><risdate>2024</risdate><abstract>The invention discloses a fish maw oligopeptide and application thereof in treating fatty liver diseases, belongs to the technical field of biology, and is used for solving the problems that a peptide fragment has antioxidant activity and fat accumulation of hepatocytes is reduced, an amino acid sequence of the fish maw oligopeptide comprises Tyr-Cys-Tyr-Cys-Pro-Arg, and a drug delivery system composed of the fish maw oligopeptide, galactosylated and modified bacterial cellulose and astaxanthin can be used for preparing the fish maw oligopeptide. The liver targeting property and delivery rate are extremely high, accumulation and peroxidation of liver cell lipid can be relieved, and alcoholic or non-alcoholic fatty liver injury can be improved.
一种花胶低聚肽及用于治疗脂肪肝疾病的应用，属于生物技术领域，用于解决肽段具有抗氧化活性，减少肝细胞的脂肪堆积问题，花胶低聚肽氨基酸序列包括Tyr-Cys-Tyr-Cys-Pro-Arg，其与半乳糖基化修饰的细菌纤维素、虾青素组成的给药体系，具有极高的肝靶向性及递送率，能够缓解肝细胞脂质的堆积与过氧化，改善酒精性或非酒精性脂肪性肝损伤。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PEPTIDES POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS THEIR PREPARATION OR CHEMICAL WORKING-UP VINEGAR WINE |
| title | Fish maw oligopeptide and application of fish maw oligopeptide to treatment of fatty liver diseases |
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