Deuterated heterocyclic compound as well as preparation method and application thereof
According to the preparation method of the deuterated heterocyclic compound, deuteration is introduced in the early stage of the synthesis route of the compound A, the conversion step of expensive raw materials in the later stage of the synthesis route is reduced, the synthesis cost of the compound...
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creator | CHEN YUELEI HE DARONG WU HAO HU ZHIGANG ZHAO HAOYING HE YONG |
description | According to the preparation method of the deuterated heterocyclic compound, deuteration is introduced in the early stage of the synthesis route of the compound A, the conversion step of expensive raw materials in the later stage of the synthesis route is reduced, the synthesis cost of the compound A is remarkably reduced, the yield is high, the process is simple, and the raw materials are easy to obtain. On the basis, the inventor completes the invention.
本发明提供一种氘代杂环化合物的制备方法,该方法在化合物A的合成路线前期即引入氘代,有利于减少合成路线后期昂贵原料的转化步骤,显著降低化合物A的合成成本,且产率高、工艺简单原料易得。在此基础上,发明人完成了本发明。 |
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本发明提供一种氘代杂环化合物的制备方法,该方法在化合物A的合成路线前期即引入氘代,有利于减少合成路线后期昂贵原料的转化步骤,显著降低化合物A的合成成本,且产率高、工艺简单原料易得。在此基础上,发明人完成了本发明。</description><language>chi ; eng</language><subject>APPARATUS THEREFOR ; CHEMISTRY ; DERIVATIVES THEREOF ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; SUGARS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231208&DB=EPODOC&CC=CN&NR=117186103A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231208&DB=EPODOC&CC=CN&NR=117186103A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN YUELEI</creatorcontrib><creatorcontrib>HE DARONG</creatorcontrib><creatorcontrib>WU HAO</creatorcontrib><creatorcontrib>HU ZHIGANG</creatorcontrib><creatorcontrib>ZHAO HAOYING</creatorcontrib><creatorcontrib>HE YONG</creatorcontrib><title>Deuterated heterocyclic compound as well as preparation method and application thereof</title><description>According to the preparation method of the deuterated heterocyclic compound, deuteration is introduced in the early stage of the synthesis route of the compound A, the conversion step of expensive raw materials in the later stage of the synthesis route is reduced, the synthesis cost of the compound A is remarkably reduced, the yield is high, the process is simple, and the raw materials are easy to obtain. On the basis, the inventor completes the invention.
本发明提供一种氘代杂环化合物的制备方法,该方法在化合物A的合成路线前期即引入氘代,有利于减少合成路线后期昂贵原料的转化步骤,显著降低化合物A的合成成本,且产率高、工艺简单原料易得。在此基础上,发明人完成了本发明。</description><subject>APPARATUS THEREFOR</subject><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>GENERAL METHODS OF ORGANIC CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAhzSS0tSS1KLElNUchIBbLykyuTczKTFZLzcwvyS_NSFBKLFcpTc3JAdEFRakEiUG1mfp5CbmpJRj5QFqSioACoAyJckpFalJqfxsPAmpaYU5zKC6W5GRTdXEOcPXRTC_LjU4sLEpNT81JL4p39DA3NDS3MDA2MHY2JUQMAaUs6FQ</recordid><startdate>20231208</startdate><enddate>20231208</enddate><creator>CHEN YUELEI</creator><creator>HE DARONG</creator><creator>WU HAO</creator><creator>HU ZHIGANG</creator><creator>ZHAO HAOYING</creator><creator>HE YONG</creator><scope>EVB</scope></search><sort><creationdate>20231208</creationdate><title>Deuterated heterocyclic compound as well as preparation method and application thereof</title><author>CHEN YUELEI ; HE DARONG ; WU HAO ; HU ZHIGANG ; ZHAO HAOYING ; HE YONG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN117186103A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>APPARATUS THEREFOR</topic><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>GENERAL METHODS OF ORGANIC CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEN YUELEI</creatorcontrib><creatorcontrib>HE DARONG</creatorcontrib><creatorcontrib>WU HAO</creatorcontrib><creatorcontrib>HU ZHIGANG</creatorcontrib><creatorcontrib>ZHAO HAOYING</creatorcontrib><creatorcontrib>HE YONG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEN YUELEI</au><au>HE DARONG</au><au>WU HAO</au><au>HU ZHIGANG</au><au>ZHAO HAOYING</au><au>HE YONG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Deuterated heterocyclic compound as well as preparation method and application thereof</title><date>2023-12-08</date><risdate>2023</risdate><abstract>According to the preparation method of the deuterated heterocyclic compound, deuteration is introduced in the early stage of the synthesis route of the compound A, the conversion step of expensive raw materials in the later stage of the synthesis route is reduced, the synthesis cost of the compound A is remarkably reduced, the yield is high, the process is simple, and the raw materials are easy to obtain. On the basis, the inventor completes the invention.
本发明提供一种氘代杂环化合物的制备方法,该方法在化合物A的合成路线前期即引入氘代,有利于减少合成路线后期昂贵原料的转化步骤,显著降低化合物A的合成成本,且产率高、工艺简单原料易得。在此基础上,发明人完成了本发明。</abstract><oa>free_for_read</oa></addata></record> |
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subjects | APPARATUS THEREFOR CHEMISTRY DERIVATIVES THEREOF GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS |
title | Deuterated heterocyclic compound as well as preparation method and application thereof |
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