Extracting agent for extracting carbamazepine in saliva

The invention discloses an extracting agent for extracting carbamazepine in saliva, and relates to the technical field of extracting agents. The extracting agent for extracting carbamazepine in saliva is formed by mixing sodium chloride and an organic solvent, the mass percentage of sodium chloride...

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Bibliographische Detailangaben
Hauptverfasser: TANG KEQI, LIU ZEYUAN, SUN MENGNI, YU JIANCHENG, TANG XU, ZHANG TIANHAN, WANG XINYAO
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses an extracting agent for extracting carbamazepine in saliva, and relates to the technical field of extracting agents. The extracting agent for extracting carbamazepine in saliva is formed by mixing sodium chloride and an organic solvent, the mass percentage of sodium chloride in the extracting agent is 5%-10%, and the organic solvent is a mixture of trichloromethane and formic acid. The extraction agent is directly added into unpretreated saliva for extraction, and after vortex extraction, the supernatant is removed to obtain the extracted carbamazepine sample, so that the extraction cost and the operation difficulty of carbamazepine are reduced. 本发明公开了一种用于唾液中卡马西平提取的萃取剂,涉及萃取剂技术领域。本发明用于唾液中卡马西平提取的萃取剂是由氯化钠和有机溶剂混合而成,其中氯化钠在所述萃取剂中的质量百分数为5%~10%,所述有机溶剂为三氯甲烷和甲酸的混合物。本发明萃取剂直接添加到未经过前处理的唾液中进行萃取,经过涡旋萃取后,去除上清即可得到提取的卡马西平样本,降低了卡马西平萃取成本和操作难度。