Broad-spectrum antibody of SARS-CoV-2 virus and application thereof

The invention relates to a broad-spectrum antibody of an SARS-CoV-2 virus, and the broad-spectrum antibody can be combined with S protein on the SARS-CoV-2 virus, so as to block cytopathy caused by the SARS-CoV-2 virus or neutralize the SARS-CoV-2 virus. The invention also relates to a nucleic acid...

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Hauptverfasser: YU BEIBEI, DOU CHANGLIN, FENG JIANXIA, RAO MUDING, ZHANG YA'NAN, LIU HONG, DONG CHUANGCHUANG, XING PINGPING, SONG DEYONG, WANG YIYUN, HU FENGJUAN
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creator YU BEIBEI
DOU CHANGLIN
FENG JIANXIA
RAO MUDING
ZHANG YA'NAN
LIU HONG
DONG CHUANGCHUANG
XING PINGPING
SONG DEYONG
WANG YIYUN
HU FENGJUAN
description The invention relates to a broad-spectrum antibody of an SARS-CoV-2 virus, and the broad-spectrum antibody can be combined with S protein on the SARS-CoV-2 virus, so as to block cytopathy caused by the SARS-CoV-2 virus or neutralize the SARS-CoV-2 virus. The invention also relates to a nucleic acid encoding the broad-spectrum antibody or the antigen binding fragment thereof; a cell containing the nucleic acid; a pharmaceutical composition containing the broad-spectrum antibody or the antigen binding fragment thereof, the nucleic acid, and the cell; a kit containing the broad-spectrum antibody or the antigen binding fragment thereof, the nucleic acid, and the pharmaceutical composition; the invention also discloses application of the broad-spectrum antibody or the antigen binding fragment thereof, the nucleic acid and the pharmaceutical composition in prevention, treatment, detection or diagnosis of diseases related to the SARS-CoV-2 virus. 本发明涉及一种SARS-CoV-2病毒的广谱抗体,所述广谱抗体能结合SARS-CoV-2病毒上的S蛋白,阻断SARS-CoV-2病毒引起的细
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The invention also relates to a nucleic acid encoding the broad-spectrum antibody or the antigen binding fragment thereof; a cell containing the nucleic acid; a pharmaceutical composition containing the broad-spectrum antibody or the antigen binding fragment thereof, the nucleic acid, and the cell; a kit containing the broad-spectrum antibody or the antigen binding fragment thereof, the nucleic acid, and the pharmaceutical composition; the invention also discloses application of the broad-spectrum antibody or the antigen binding fragment thereof, the nucleic acid and the pharmaceutical composition in prevention, treatment, detection or diagnosis of diseases related to the SARS-CoV-2 virus. 本发明涉及一种SARS-CoV-2病毒的广谱抗体,所述广谱抗体能结合SARS-CoV-2病毒上的S蛋白,阻断SARS-CoV-2病毒引起的细</description><language>chi ; eng</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20231027&amp;DB=EPODOC&amp;CC=CN&amp;NR=116964103A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20231027&amp;DB=EPODOC&amp;CC=CN&amp;NR=116964103A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YU BEIBEI</creatorcontrib><creatorcontrib>DOU CHANGLIN</creatorcontrib><creatorcontrib>FENG JIANXIA</creatorcontrib><creatorcontrib>RAO MUDING</creatorcontrib><creatorcontrib>ZHANG YA'NAN</creatorcontrib><creatorcontrib>LIU HONG</creatorcontrib><creatorcontrib>DONG CHUANGCHUANG</creatorcontrib><creatorcontrib>XING PINGPING</creatorcontrib><creatorcontrib>SONG DEYONG</creatorcontrib><creatorcontrib>WANG YIYUN</creatorcontrib><creatorcontrib>HU FENGJUAN</creatorcontrib><title>Broad-spectrum antibody of SARS-CoV-2 virus and application thereof</title><description>The invention relates to a broad-spectrum antibody of an SARS-CoV-2 virus, and the broad-spectrum antibody can be combined with S protein on the SARS-CoV-2 virus, so as to block cytopathy caused by the SARS-CoV-2 virus or neutralize the SARS-CoV-2 virus. 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METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title Broad-spectrum antibody of SARS-CoV-2 virus and application thereof
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