Application of DERL1 gene promoter region methylation site in esophageal cancer diagnosis

The invention belongs to the technical field of biological medicines, and particularly relates to application of DERL1 gene promoter region methylation sites in esophageal cancer diagnosis. By detecting the expression level of DERL1 gene promoter region methylation sites in esophageal cancer tissues and paracancerous normal tissues or the expression level of DERL1 genes, it is indicated that the average methylation level in esophageal squamous cell carcinoma tissues is lower than that in the paracancerous normal tissues, and the difference has statistical significance; meanwhile, the expression of the DERL1 protein in the esophageal squamous carcinoma is obviously higher than that of para-carcinoma normal tissues, and the difference has statistical significance. Therefore, the DERL1 gene or the DERL1 gene promoter region methylation site in the esophageal cancer can be used for diagnosis, adjuvant therapy and prognosis evaluation of the esophageal cancer as a detection marker. 本发明属于生物医药技术领域，具体涉及DERL1基因启动子区甲基化