Method for preparing staphylococcus aureus pneumonia mouse model and model evaluation

The invention discloses a method for preparing a staphylococcus aureus pneumonia mouse model and model evaluation. The method comprises the following steps: step 1, marking staphylococcus aureus in vitro; step 2, establishment of a staphylococcus aureus pneumonia mouse model: by adopting a mode of exposing a trachea and atomizing bacteria by a quantitative aerosol atomizing device in the trachea of the mouse through an oral trachea, the amount inhaled by the mouse can be controlled at the same level, the error of each group is smaller, and the modeling quality is higher; the lung imaging condition of the mouse is observed in vivo through a near-infrared imaging system, the mouse is successfully modeled when the mouse lung has an obvious and uniform near-infrared fluorescence image, whether the model is successfully established or not can be known at the first time, the hysteresis is avoided, and the modeling success rate can be effectively improved. And the evaluation method does not need a series of invasive