Japanese encephalitis vaccine as well as preparation method and application thereof

Japanese encephalitis vaccine as well as preparation method and application thereof

The invention discloses a Japanese encephalitis E recombinant protein, the Japanese encephalitis E recombinant protein comprises a Japanese encephalitis E recombinant protein 1 and a Japanese encephalitis E recombinant protein 2, the amino acid sequence of the Japanese encephalitis E recombinant pro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MA GUIJUN, GENG KAITONG
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention discloses a Japanese encephalitis E recombinant protein, the Japanese encephalitis E recombinant protein comprises a Japanese encephalitis E recombinant protein 1 and a Japanese encephalitis E recombinant protein 2, the amino acid sequence of the Japanese encephalitis E recombinant protein 1 is as shown in SEQ ID NO.1, and the amino acid sequence of the Japanese encephalitis E recombinant protein 2 is as shown in SEQ ID NO.3. The invention also discloses a Japanese encephalitis subunit vaccine. The vaccine contains the Japanese encephalitis E recombinant protein 1 or the Japanese encephalitis E recombinant protein 2. The Japanese encephalitis E recombinant protein 1 and the Japanese encephalitis E recombinant protein 2 prepared by the invention have good immunogenicity, and the Japanese encephalitis E recombinant protein 2 has better immunogenicity than the Japanese encephalitis E recombinant protein 1. Therefore, the two Japanese encephalitis E recombinant proteins disclosed by the invention ca