Application of crotonylation modified peripheral blood mononuclear cell

The invention relates to an application of a crotonylation modified peripheral blood mononuclear cell, belongs to the technical field of molecular biology, and solves the technical problem that an early-stage specific diagnostic marker with relatively small invasiveness needs to be found urgently in the current CRC laboratory diagnosis process, and the solution comprises the following steps: S1, collecting a plurality of groups of in-vitro peripheral blood mononuclear cell samples; s2, protein extraction and concentration determination; s3, carrying out a Western Blot experiment on the crotonylated ubiquitous antibody; s4, protein crotonylation level difference comparison; and S5, calculating the diagnosis efficiency of the PBMC crotonylation level. According to the invention, peripheral blood mononuclear cell crotonylation is used as a marker for detecting colorectal cancer, and compared with other invasive examinations, a feasible scheme for colorectal cancer early screening based on blood outside a colonos