Benzodihydropyran-4-one Schiff base compound and application thereof

The invention discloses a benzodihydropyran-4-ketone Schiff base compound and an application thereof. The invention discloses a new application of the benzodihydropyran-4-ketone Schiff base compound, namely the benzodihydropyran-4-ketone Schiff base compound and a derivative of the benzodihydropyran-4-ketone Schiff base compound. It is found that the compound has a good inhibition effect on mycobacterium tuberculosis, mycobacterium tuberculosis is killed by inhibiting mycobacterium tuberculosis KatG enzyme, and the compound has a good application prospect in preparation of anti-tuberculosis drugs. 本发明公布了一种苯并二氢吡喃-4-酮席夫碱类化合物及应用，本发明发现一类化合物的新用途：苯并二氢吡喃-4-酮席夫碱类化合物及其衍生物。本发明发现该类化合物对结核分枝杆菌有良好的抑制作用，通过抑制结核杆菌KatG酶杀死结核杆菌，在制备抗结核药物中具有很好的应用前景。