Hapten and artificial antigen for simultaneously detecting various nafil drugs in food and application of hapten and artificial antigen

The invention discloses a hapten and an artificial antigen for simultaneously detecting various nafil drugs in food and application of the hapten and the artificial antigen. The two haptens for broad-spectrum detection of the nafil drugs are provided, the artificial antigen and the antibody for broa...

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Hauptverfasser: LEI HONGTAO, PAN KANGLIANG, CHEN JIAHONG, GUAN MINGTONG, LIU ZHIWEI, GUAN TIAN, XU ZHENLIN
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creator LEI HONGTAO
PAN KANGLIANG
CHEN JIAHONG
GUAN MINGTONG
LIU ZHIWEI
GUAN TIAN
XU ZHENLIN
description The invention discloses a hapten and an artificial antigen for simultaneously detecting various nafil drugs in food and application of the hapten and the artificial antigen. The two haptens for broad-spectrum detection of the nafil drugs are provided, the artificial antigen and the antibody for broad-spectrum detection of the nafil drugs are prepared from the haptens, and the obtained antibody is high in titer, high in detection sensitivity, wide in linear range and capable of recognizing various nafil drugs. The hapten and the artificial antigen for broad-spectrum detection of the nafil drugs, provided by the invention, can be effectively used for rapid detection of the nafil drugs, and have a good popularization value and a wide application prospect. 本发明公开了一种用于食品中多种那非类药物同时检测的半抗原、人工抗原及其应用。本发明提供了两种用于广谱检测那非类药物的半抗原,并应用该半抗原制备得到了用于广谱检测那非类药物的人工抗原和抗体,所得抗体效价高,检测灵敏度高,线性范围广,可识别多种那非类药物。本发明提供的用于广谱检测那非类药物的半抗原和人工抗原能有效用于检测那非类药物的快速检测,具有良好的推广价值和广阔的应用前景。
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The hapten and the artificial antigen for broad-spectrum detection of the nafil drugs, provided by the invention, can be effectively used for rapid detection of the nafil drugs, and have a good popularization value and a wide application prospect. 本发明公开了一种用于食品中多种那非类药物同时检测的半抗原、人工抗原及其应用。本发明提供了两种用于广谱检测那非类药物的半抗原,并应用该半抗原制备得到了用于广谱检测那非类药物的人工抗原和抗体,所得抗体效价高,检测灵敏度高,线性范围广,可识别多种那非类药物。本发明提供的用于广谱检测那非类药物的半抗原和人工抗原能有效用于检测那非类药物的快速检测,具有良好的推广价值和广阔的应用前景。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; TESTING</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230714&amp;DB=EPODOC&amp;CC=CN&amp;NR=116425759A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230714&amp;DB=EPODOC&amp;CC=CN&amp;NR=116425759A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEI HONGTAO</creatorcontrib><creatorcontrib>PAN KANGLIANG</creatorcontrib><creatorcontrib>CHEN JIAHONG</creatorcontrib><creatorcontrib>GUAN MINGTONG</creatorcontrib><creatorcontrib>LIU ZHIWEI</creatorcontrib><creatorcontrib>GUAN TIAN</creatorcontrib><creatorcontrib>XU ZHENLIN</creatorcontrib><title>Hapten and artificial antigen for simultaneously detecting various nafil drugs in food and application of hapten and artificial antigen</title><description>The invention discloses a hapten and an artificial antigen for simultaneously detecting various nafil drugs in food and application of the hapten and the artificial antigen. 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The two haptens for broad-spectrum detection of the nafil drugs are provided, the artificial antigen and the antibody for broad-spectrum detection of the nafil drugs are prepared from the haptens, and the obtained antibody is high in titer, high in detection sensitivity, wide in linear range and capable of recognizing various nafil drugs. The hapten and the artificial antigen for broad-spectrum detection of the nafil drugs, provided by the invention, can be effectively used for rapid detection of the nafil drugs, and have a good popularization value and a wide application prospect. 本发明公开了一种用于食品中多种那非类药物同时检测的半抗原、人工抗原及其应用。本发明提供了两种用于广谱检测那非类药物的半抗原,并应用该半抗原制备得到了用于广谱检测那非类药物的人工抗原和抗体,所得抗体效价高,检测灵敏度高,线性范围广,可识别多种那非类药物。本发明提供的用于广谱检测那非类药物的半抗原和人工抗原能有效用于检测那非类药物的快速检测,具有良好的推广价值和广阔的应用前景。</abstract><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
title Hapten and artificial antigen for simultaneously detecting various nafil drugs in food and application of hapten and artificial antigen
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