Bicyclic heteroaryl compounds and uses thereof
The present disclosure is directed to SOS1 modulators and their use for the treatment of disease. Also disclosed are pharmaceutical compositions comprising the SOS1 modulators. 本公开针对SOS1调节剂及其用于治疗疾病的用途。还公开了包含所述SOS1调节剂的药物组合物。
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| creator | BURNETT G. LESLIE COTTON EDWARD SCOTT A. V. EDWARDS AYE NEIL LIU YIHAN GILL ADRIAN LIAM THOMPSON SARAH CREGG JAMES JOSEPH TANBOYON AMNON A GITTER MICHAEL J THOMAS WILLIAM D KNOX JOHN E BUCK ALEXANDER |
| description | The present disclosure is directed to SOS1 modulators and their use for the treatment of disease. Also disclosed are pharmaceutical compositions comprising the SOS1 modulators.
本公开针对SOS1调节剂及其用于治疗疾病的用途。还公开了包含所述SOS1调节剂的药物组合物。 |
| format | Patent |
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本公开针对SOS1调节剂及其用于治疗疾病的用途。还公开了包含所述SOS1调节剂的药物组合物。</description><language>chi ; eng</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230714&DB=EPODOC&CC=CN&NR=116425742A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230714&DB=EPODOC&CC=CN&NR=116425742A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BURNETT G. LESLIE</creatorcontrib><creatorcontrib>COTTON EDWARD SCOTT</creatorcontrib><creatorcontrib>A. V. EDWARDS</creatorcontrib><creatorcontrib>AYE NEIL</creatorcontrib><creatorcontrib>LIU YIHAN</creatorcontrib><creatorcontrib>GILL ADRIAN LIAM</creatorcontrib><creatorcontrib>THOMPSON SARAH</creatorcontrib><creatorcontrib>CREGG JAMES JOSEPH</creatorcontrib><creatorcontrib>TANBOYON AMNON A</creatorcontrib><creatorcontrib>GITTER MICHAEL J</creatorcontrib><creatorcontrib>THOMAS WILLIAM D</creatorcontrib><creatorcontrib>KNOX JOHN E</creatorcontrib><creatorcontrib>BUCK ALEXANDER</creatorcontrib><title>Bicyclic heteroaryl compounds and uses thereof</title><description>The present disclosure is directed to SOS1 modulators and their use for the treatment of disease. Also disclosed are pharmaceutical compositions comprising the SOS1 modulators.
本公开针对SOS1调节剂及其用于治疗疾病的用途。还公开了包含所述SOS1调节剂的药物组合物。</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNBzykyuTM7JTFbISC1JLcpPLKrMUUjOzy3IL81LKVZIzEtRKC1OLVYoyUgtSs1P42FgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8c5-hoZmJkam5iZGjsbEqAEAGJ8qzg</recordid><startdate>20230714</startdate><enddate>20230714</enddate><creator>BURNETT G. LESLIE</creator><creator>COTTON EDWARD SCOTT</creator><creator>A. V. EDWARDS</creator><creator>AYE NEIL</creator><creator>LIU YIHAN</creator><creator>GILL ADRIAN LIAM</creator><creator>THOMPSON SARAH</creator><creator>CREGG JAMES JOSEPH</creator><creator>TANBOYON AMNON A</creator><creator>GITTER MICHAEL J</creator><creator>THOMAS WILLIAM D</creator><creator>KNOX JOHN E</creator><creator>BUCK ALEXANDER</creator><scope>EVB</scope></search><sort><creationdate>20230714</creationdate><title>Bicyclic heteroaryl compounds and uses thereof</title><author>BURNETT G. LESLIE ; COTTON EDWARD SCOTT ; A. V. EDWARDS ; AYE NEIL ; LIU YIHAN ; GILL ADRIAN LIAM ; THOMPSON SARAH ; CREGG JAMES JOSEPH ; TANBOYON AMNON A ; GITTER MICHAEL J ; THOMAS WILLIAM D ; KNOX JOHN E ; BUCK ALEXANDER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN116425742A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BURNETT G. LESLIE</creatorcontrib><creatorcontrib>COTTON EDWARD SCOTT</creatorcontrib><creatorcontrib>A. V. EDWARDS</creatorcontrib><creatorcontrib>AYE NEIL</creatorcontrib><creatorcontrib>LIU YIHAN</creatorcontrib><creatorcontrib>GILL ADRIAN LIAM</creatorcontrib><creatorcontrib>THOMPSON SARAH</creatorcontrib><creatorcontrib>CREGG JAMES JOSEPH</creatorcontrib><creatorcontrib>TANBOYON AMNON A</creatorcontrib><creatorcontrib>GITTER MICHAEL J</creatorcontrib><creatorcontrib>THOMAS WILLIAM D</creatorcontrib><creatorcontrib>KNOX JOHN E</creatorcontrib><creatorcontrib>BUCK ALEXANDER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BURNETT G. LESLIE</au><au>COTTON EDWARD SCOTT</au><au>A. V. EDWARDS</au><au>AYE NEIL</au><au>LIU YIHAN</au><au>GILL ADRIAN LIAM</au><au>THOMPSON SARAH</au><au>CREGG JAMES JOSEPH</au><au>TANBOYON AMNON A</au><au>GITTER MICHAEL J</au><au>THOMAS WILLIAM D</au><au>KNOX JOHN E</au><au>BUCK ALEXANDER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Bicyclic heteroaryl compounds and uses thereof</title><date>2023-07-14</date><risdate>2023</risdate><abstract>The present disclosure is directed to SOS1 modulators and their use for the treatment of disease. Also disclosed are pharmaceutical compositions comprising the SOS1 modulators.
本公开针对SOS1调节剂及其用于治疗疾病的用途。还公开了包含所述SOS1调节剂的药物组合物。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Bicyclic heteroaryl compounds and uses thereof |
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