Preparation method of BTK degradation agent

According to the preparation method of the BTK inhibitor compound and the intermediate thereof, the reaction condition is mild, high-temperature and high-pressure reaction is not involved, raw materials are low in toxicity or non-toxic, operation is easy, the reaction yield is high, the product purity is high, aftertreatment is convenient, reproducibility is good, and the method is suitable for industrial production. 一种BTK抑制剂化合物及其中间体的制备方法，该方法反应条件温和，不涉及高温、高压反应，原材料低毒或无毒，操作简单，反应产率高，产品纯度高，后处理方便，重现性好，适合于工业化生产。