Hair analysis method for simultaneously detecting methcathinone and methcathinone metabolite

Hair analysis method for simultaneously detecting methcathinone and methcathinone metabolite

The invention relates to a hair analysis method for simultaneously detecting methcathinone and methcathinone metabolites, the methcathinone metabolites comprise cathinone, ephedrine and pseudoephedrine, and the hair analysis method comprises the following steps: cleaning a hair sample through an org...

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Hauptverfasser: ZHENG JIAMING, WANG XIN, XIANG PING, QIANG HUOSHENG, DENG HONGXIAO
Format: Patent
Sprache:chi ; eng
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INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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creator ZHENG JIAMING
WANG XIN
XIANG PING
QIANG HUOSHENG
DENG HONGXIAO
description The invention relates to a hair analysis method for simultaneously detecting methcathinone and methcathinone metabolites, the methcathinone metabolites comprise cathinone, ephedrine and pseudoephedrine, and the hair analysis method comprises the following steps: cleaning a hair sample through an organic solvent, drying at room temperature, transferring into an internal standard working solution, and detecting the methcathinone and the methcathinone metabolites at the same time. Sequentially carrying out low-temperature freezing and grinding, room-temperature dark incubation, centrifugation and microfiltration, and then feeding a sample into an LC-MS (Liquid Chromatography-Mass Spectrometer) system; the simple and sensitive UHPLC-MS/MS method is established, methcathinone and methcathinone metabolites (cathinone, ephedrine and pseudoephedrine) in hair can be qualitatively and quantitatively analyzed at the same time, chromatographic separation is good, the method is simple and convenient, good detection limit
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title Hair analysis method for simultaneously detecting methcathinone and methcathinone metabolite
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