Compound capable of stabilizing polypeptide and preparation method thereof

The invention belongs to the field of biotechnology and cosmetics, and relates to a compound capable of stabilizing polypeptide and a preparation method thereof, and the compound comprises the following components in parts by weight: 3-15 parts of trehalose, 0.5-10 parts of lecithin, 65-90 parts of glycerol, 1-10 parts of water and 0.03-1 part of cosmetic polypeptide. Compared with the prior art, the lecithin adopted by the invention is easy to form a layered liquid crystal structure, can form a hollow spherical single-layer or multi-layer liposome with a bilayer structure in an aqueous solution, and can wrap the water-soluble or water-insoluble polypeptide of the cosmetic in an internal hydrophilic layer or oleophilic layer; the preparation method has the advantages that the activity of the polypeptide is prevented from disappearing due to reaction between exposed residues of the polypeptide and external substances, meanwhile, the trehalose can be filled between the phosphatidylcholine in a liquid crystal ph