Pir B virulence protein binding peptide P2 of pathogenic vibrio and application of Pir B virulence protein binding peptide P2
The invention discloses a pathogenic vibrio Pir B virulence protein binding peptide P2 and application thereof. The small molecule binding peptide P2 has high affinity with Pir B virulence protein, and the amino acid sequence of the small molecule binding peptide P2 is LGSPLLTYGRPQ. The binding pept...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | HU CHAOQUN JIANG XIAO ZHANG LYUPING REN CHUNHUA CHEN TING LUO PENG WANG YANHONG ZHANG XIN |
| description | The invention discloses a pathogenic vibrio Pir B virulence protein binding peptide P2 and application thereof. The small molecule binding peptide P2 has high affinity with Pir B virulence protein, and the amino acid sequence of the small molecule binding peptide P2 is LGSPLLTYGRPQ. The binding peptide with high affinity with pathogenic vibrio Pir B virulence protein is screened from a random peptide library through a phage display technology, the binding peptide is chemically synthesized, the survival rate of prawns infected with vibrio can be effectively improved after the binding peptide is injected, and the binding peptide has a remarkable protection effect on prawn culture. The binding peptide can be efficiently combined with pathogenic vibrio PirB virulence protein, and the virulence of PirB protein is effectively reduced; in addition, the method can effectively reduce the use of antibiotics in healthy culture of the prawns, reduces the generation of drug-resistant strains, and has a good application pr |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN116130025A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN116130025A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN116130025A3</originalsourceid><addsrcrecordid>eNqNjDEKwkAQANNYiPqH9QFCLkF7DYqVpLAPm7tNXDh2l8tp599V8AGpppmZZfFuOcEJXpyekcQTWNJMLNCzBJYRjCxzIGgr0AEM80NHEvbfpE-sgBIAzSJ7zKzyk-Yv18ViwDjR5s9Vsb2c7811R6YdTYaehHLX3Jw7uLosq_2xnuN8AI-5Rs4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Pir B virulence protein binding peptide P2 of pathogenic vibrio and application of Pir B virulence protein binding peptide P2</title><source>esp@cenet</source><creator>HU CHAOQUN ; JIANG XIAO ; ZHANG LYUPING ; REN CHUNHUA ; CHEN TING ; LUO PENG ; WANG YANHONG ; ZHANG XIN</creator><creatorcontrib>HU CHAOQUN ; JIANG XIAO ; ZHANG LYUPING ; REN CHUNHUA ; CHEN TING ; LUO PENG ; WANG YANHONG ; ZHANG XIN</creatorcontrib><description>The invention discloses a pathogenic vibrio Pir B virulence protein binding peptide P2 and application thereof. The small molecule binding peptide P2 has high affinity with Pir B virulence protein, and the amino acid sequence of the small molecule binding peptide P2 is LGSPLLTYGRPQ. The binding peptide with high affinity with pathogenic vibrio Pir B virulence protein is screened from a random peptide library through a phage display technology, the binding peptide is chemically synthesized, the survival rate of prawns infected with vibrio can be effectively improved after the binding peptide is injected, and the binding peptide has a remarkable protection effect on prawn culture. The binding peptide can be efficiently combined with pathogenic vibrio PirB virulence protein, and the virulence of PirB protein is effectively reduced; in addition, the method can effectively reduce the use of antibiotics in healthy culture of the prawns, reduces the generation of drug-resistant strains, and has a good application pr</description><language>chi ; eng</language><subject>INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS ; PHYSICS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230516&DB=EPODOC&CC=CN&NR=116130025A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230516&DB=EPODOC&CC=CN&NR=116130025A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HU CHAOQUN</creatorcontrib><creatorcontrib>JIANG XIAO</creatorcontrib><creatorcontrib>ZHANG LYUPING</creatorcontrib><creatorcontrib>REN CHUNHUA</creatorcontrib><creatorcontrib>CHEN TING</creatorcontrib><creatorcontrib>LUO PENG</creatorcontrib><creatorcontrib>WANG YANHONG</creatorcontrib><creatorcontrib>ZHANG XIN</creatorcontrib><title>Pir B virulence protein binding peptide P2 of pathogenic vibrio and application of Pir B virulence protein binding peptide P2</title><description>The invention discloses a pathogenic vibrio Pir B virulence protein binding peptide P2 and application thereof. The small molecule binding peptide P2 has high affinity with Pir B virulence protein, and the amino acid sequence of the small molecule binding peptide P2 is LGSPLLTYGRPQ. The binding peptide with high affinity with pathogenic vibrio Pir B virulence protein is screened from a random peptide library through a phage display technology, the binding peptide is chemically synthesized, the survival rate of prawns infected with vibrio can be effectively improved after the binding peptide is injected, and the binding peptide has a remarkable protection effect on prawn culture. The binding peptide can be efficiently combined with pathogenic vibrio PirB virulence protein, and the virulence of PirB protein is effectively reduced; in addition, the method can effectively reduce the use of antibiotics in healthy culture of the prawns, reduces the generation of drug-resistant strains, and has a good application pr</description><subject>INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS</subject><subject>PHYSICS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDEKwkAQANNYiPqH9QFCLkF7DYqVpLAPm7tNXDh2l8tp599V8AGpppmZZfFuOcEJXpyekcQTWNJMLNCzBJYRjCxzIGgr0AEM80NHEvbfpE-sgBIAzSJ7zKzyk-Yv18ViwDjR5s9Vsb2c7811R6YdTYaehHLX3Jw7uLosq_2xnuN8AI-5Rs4</recordid><startdate>20230516</startdate><enddate>20230516</enddate><creator>HU CHAOQUN</creator><creator>JIANG XIAO</creator><creator>ZHANG LYUPING</creator><creator>REN CHUNHUA</creator><creator>CHEN TING</creator><creator>LUO PENG</creator><creator>WANG YANHONG</creator><creator>ZHANG XIN</creator><scope>EVB</scope></search><sort><creationdate>20230516</creationdate><title>Pir B virulence protein binding peptide P2 of pathogenic vibrio and application of Pir B virulence protein binding peptide P2</title><author>HU CHAOQUN ; JIANG XIAO ; ZHANG LYUPING ; REN CHUNHUA ; CHEN TING ; LUO PENG ; WANG YANHONG ; ZHANG XIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN116130025A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS</topic><topic>PHYSICS</topic><toplevel>online_resources</toplevel><creatorcontrib>HU CHAOQUN</creatorcontrib><creatorcontrib>JIANG XIAO</creatorcontrib><creatorcontrib>ZHANG LYUPING</creatorcontrib><creatorcontrib>REN CHUNHUA</creatorcontrib><creatorcontrib>CHEN TING</creatorcontrib><creatorcontrib>LUO PENG</creatorcontrib><creatorcontrib>WANG YANHONG</creatorcontrib><creatorcontrib>ZHANG XIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HU CHAOQUN</au><au>JIANG XIAO</au><au>ZHANG LYUPING</au><au>REN CHUNHUA</au><au>CHEN TING</au><au>LUO PENG</au><au>WANG YANHONG</au><au>ZHANG XIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pir B virulence protein binding peptide P2 of pathogenic vibrio and application of Pir B virulence protein binding peptide P2</title><date>2023-05-16</date><risdate>2023</risdate><abstract>The invention discloses a pathogenic vibrio Pir B virulence protein binding peptide P2 and application thereof. The small molecule binding peptide P2 has high affinity with Pir B virulence protein, and the amino acid sequence of the small molecule binding peptide P2 is LGSPLLTYGRPQ. The binding peptide with high affinity with pathogenic vibrio Pir B virulence protein is screened from a random peptide library through a phage display technology, the binding peptide is chemically synthesized, the survival rate of prawns infected with vibrio can be effectively improved after the binding peptide is injected, and the binding peptide has a remarkable protection effect on prawn culture. The binding peptide can be efficiently combined with pathogenic vibrio PirB virulence protein, and the virulence of PirB protein is effectively reduced; in addition, the method can effectively reduce the use of antibiotics in healthy culture of the prawns, reduces the generation of drug-resistant strains, and has a good application pr</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng |
| recordid | cdi_epo_espacenet_CN116130025A |
| source | esp@cenet |
| subjects | INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS PHYSICS |
| title | Pir B virulence protein binding peptide P2 of pathogenic vibrio and application of Pir B virulence protein binding peptide P2 |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T06%3A40%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=HU%20CHAOQUN&rft.date=2023-05-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN116130025A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |