IL-2 mutant immunoconjugates

The invention relates to an immunoconjugate of an anti-PD1 antibody and an IL-2 mutant. The immunoconjugate comprises an interleukin 2 (IL-2) polypeptide mutant and an antibody or an antigen binding fragment which binds to PD1. Polynucleotides encoding the immunoconjugates, expression vectors, host...

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Bibliographische Detailangaben
Hauptverfasser:	HUANG RUI, RAO MUDING, DOU CHANGLIN, PAN RONGRONG, WANG QIAOPING, XING PINGPING, SONG DEYONG, JIAO JIE
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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