Two-component sealing system comprising synthetic matrix and biosynthetic adhesive for sealing resected surface of organ to control bleeding, fluid leakage and air leakage

A method of sealing a resected surface of an organ, the method comprising applying a synthetic matrix to a resected surface of an organ, and applying an adhesive on the synthetic matrix such that the adhesive permeates through a gap of the synthetic matrix to contact an interface between the synthetic matrix and the resected surface of the organ. The method includes curing the adhesive to bond the synthetic matrix to the resected surface of the organ. The synthetic matrix is a non-woven patch made of polyglycolide lactide 910 or any other synthetic or non-synthetic fabric having a similar porosity or density. The adhesive is a biosynthetic or synthetic adhesive. After penetrating through the pores of the synthetic matrix and curing, the cured biosynthetic or synthetic adhesive mechanically interlocks with the synthetic matrix to adhere the synthetic matrix to the tissue, thereby creating a sealing barrier. 一种密封器官的切除表面的方法，该方法包括将合成基质施加到器官的切除表面，以及将粘合剂施加在该合成基质上，使得该粘合剂渗透穿过该合成基质的间隙以接触该合成基质与该器官的该切除表面之间的界面。该方法包括固化该粘合