Masked IL-15 cytokines and cleavage products thereof

The present invention relates to a masked IL-15 cytokine comprising an IL-15 cytokine or a functional fragment thereof, a masking moiety, and a proteolytically cleavable linker. The cleavable linker has a masking portion that masks the IL-15 cytokine or functional fragment thereof, thereby reducing...

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Bibliographische Detailangaben
Hauptverfasser: ROSENFELD REVITAL, ESKIOUCAK, UMIT, PODZOLLI-RIEBEL MARTINA, O 'DONNELL RICHARD KEVIN, JOHNSON, PAUL, QIU HUAWEI, TOMA DANIEL S, JENKINS KURT A
Format: Patent
Sprache:chi ; eng
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