Recombinant NMDA receptor protein and application thereof

The invention relates to the technical field of biotechnology, and particularly discloses a recombinant NMDA receptor protein and application thereof, and the recombinant NMDA receptor protein comprises an amino acid sequence as shown in SEQ ID No.1. The invention further provides a cell for stable...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: ZHU JINGSHAN
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator ZHU JINGSHAN
description The invention relates to the technical field of biotechnology, and particularly discloses a recombinant NMDA receptor protein and application thereof, and the recombinant NMDA receptor protein comprises an amino acid sequence as shown in SEQ ID No.1. The invention further provides a cell for stable overexpression of the recombinant NMDA receptor protein, and the cell is applied to preparation of an anti-NMDA receptor antibody encephalitis detection product. By combining the core sequence of the HSP70 protein with the complete sequence of the NMDA receptor protein, the expression quantity of the constructed recombinant NMDA receptor protein is higher, and the binding capacity with the anti-NMDA receptor antibody is higher. The binding efficiency of the cell for stably overexpressing the recombinant NMDA receptor and the anti-NMDA receptor antibody is higher, the sensitivity of the detection reaction is further improved, and the detection result is more accurate. 本申请涉及生物技术的技术领域,具体公开了一种重组NMDA受体蛋白及其应用,所述重组NMDA受体蛋
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN115850513A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN115850513A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN115850513A3</originalsourceid><addsrcrecordid>eNrjZLAMSk3Oz03KzEvMK1Hw83VxVChKTU4tKMkvUigoyi9JzcxTSMxLUUgsKMjJTE4syczPUyjJSC1KzU_jYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxzn6GhqYWpgamhsaOxsSoAQAo8S6F</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Recombinant NMDA receptor protein and application thereof</title><source>esp@cenet</source><creator>ZHU JINGSHAN</creator><creatorcontrib>ZHU JINGSHAN</creatorcontrib><description>The invention relates to the technical field of biotechnology, and particularly discloses a recombinant NMDA receptor protein and application thereof, and the recombinant NMDA receptor protein comprises an amino acid sequence as shown in SEQ ID No.1. The invention further provides a cell for stable overexpression of the recombinant NMDA receptor protein, and the cell is applied to preparation of an anti-NMDA receptor antibody encephalitis detection product. By combining the core sequence of the HSP70 protein with the complete sequence of the NMDA receptor protein, the expression quantity of the constructed recombinant NMDA receptor protein is higher, and the binding capacity with the anti-NMDA receptor antibody is higher. The binding efficiency of the cell for stably overexpressing the recombinant NMDA receptor and the anti-NMDA receptor antibody is higher, the sensitivity of the detection reaction is further improved, and the detection result is more accurate. 本申请涉及生物技术的技术领域,具体公开了一种重组NMDA受体蛋白及其应用,所述重组NMDA受体蛋</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230328&amp;DB=EPODOC&amp;CC=CN&amp;NR=115850513A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230328&amp;DB=EPODOC&amp;CC=CN&amp;NR=115850513A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHU JINGSHAN</creatorcontrib><title>Recombinant NMDA receptor protein and application thereof</title><description>The invention relates to the technical field of biotechnology, and particularly discloses a recombinant NMDA receptor protein and application thereof, and the recombinant NMDA receptor protein comprises an amino acid sequence as shown in SEQ ID No.1. The invention further provides a cell for stable overexpression of the recombinant NMDA receptor protein, and the cell is applied to preparation of an anti-NMDA receptor antibody encephalitis detection product. By combining the core sequence of the HSP70 protein with the complete sequence of the NMDA receptor protein, the expression quantity of the constructed recombinant NMDA receptor protein is higher, and the binding capacity with the anti-NMDA receptor antibody is higher. The binding efficiency of the cell for stably overexpressing the recombinant NMDA receptor and the anti-NMDA receptor antibody is higher, the sensitivity of the detection reaction is further improved, and the detection result is more accurate. 本申请涉及生物技术的技术领域,具体公开了一种重组NMDA受体蛋白及其应用,所述重组NMDA受体蛋</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAMSk3Oz03KzEvMK1Hw83VxVChKTU4tKMkvUigoyi9JzcxTSMxLUUgsKMjJTE4syczPUyjJSC1KzU_jYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxzn6GhqYWpgamhsaOxsSoAQAo8S6F</recordid><startdate>20230328</startdate><enddate>20230328</enddate><creator>ZHU JINGSHAN</creator><scope>EVB</scope></search><sort><creationdate>20230328</creationdate><title>Recombinant NMDA receptor protein and application thereof</title><author>ZHU JINGSHAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115850513A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHU JINGSHAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHU JINGSHAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Recombinant NMDA receptor protein and application thereof</title><date>2023-03-28</date><risdate>2023</risdate><abstract>The invention relates to the technical field of biotechnology, and particularly discloses a recombinant NMDA receptor protein and application thereof, and the recombinant NMDA receptor protein comprises an amino acid sequence as shown in SEQ ID No.1. The invention further provides a cell for stable overexpression of the recombinant NMDA receptor protein, and the cell is applied to preparation of an anti-NMDA receptor antibody encephalitis detection product. By combining the core sequence of the HSP70 protein with the complete sequence of the NMDA receptor protein, the expression quantity of the constructed recombinant NMDA receptor protein is higher, and the binding capacity with the anti-NMDA receptor antibody is higher. The binding efficiency of the cell for stably overexpressing the recombinant NMDA receptor and the anti-NMDA receptor antibody is higher, the sensitivity of the detection reaction is further improved, and the detection result is more accurate. 本申请涉及生物技术的技术领域,具体公开了一种重组NMDA受体蛋白及其应用,所述重组NMDA受体蛋</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language chi ; eng
recordid cdi_epo_espacenet_CN115850513A
source esp@cenet
subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
title Recombinant NMDA receptor protein and application thereof
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T08%3A05%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ZHU%20JINGSHAN&rft.date=2023-03-28&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN115850513A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true