Growth hormone FC fusion protein injection and application thereof

The invention relates to a composition containing growth hormone fusion protein and application thereof. The composition comprises growth hormone fusion protein and at least one of a buffering agent and a protective agent, the composition is applied to preparation of drugs for treating and/or preventing growth hormone abnormality related diseases. The composition provided by the invention can reduce or inhibit the generation of molecular fragments, and improves the stability of the growth hormone fusion protein in the preparation and storage processes; moreover, the composition does not need a complex preparation process, can be directly prepared into an injection with high stability, and has better long-acting pharmacokinetic characteristics. 本发明涉及了一种含有生长激素融合蛋白的组合物及其用途。所述组合物包括：生长激素融合蛋白，以及缓冲剂和保护剂中的至少之一；上述组合物在制备用于治疗和/或预防生长激素异常相关疾病的药物中的用途。本发明的组合物可减少或抑制分子碎片的产生，在制备和贮藏过程中，提高生长激素融合蛋白的稳定性；并且，该组合物不需复杂的制备工艺，可直接制备成稳定性高的注射液，且具有较好的长效药代动力学特征。