Proteins that bind NKG2D, CD16 and CLEC12A

Proteins that bind NKG2D, CD16 and CLEC12A

Described herein are multispecific binding proteins that bind to the NKG2D receptor, CD16, and CLEC12A, pharmaceutical compositions comprising these multispecific binding proteins, and therapeutic methods useful for the treatment of cancer. 本文描述了结合NKG2D受体、CD16和CLEC12A的多特异性结合蛋白，包含这些多特异性结合蛋白的药物组合物，以及可...

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Bibliographische Detailangaben
Hauptverfasser: FALLON DENIS, CHANG, GEORGE, P, CHEUNG, ALBERT, F, MORGAN CHRISTOPHER RYAN, BARUAH HASSAN, JUDE ZACHARY S, GRINBERG ASYA
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:Described herein are multispecific binding proteins that bind to the NKG2D receptor, CD16, and CLEC12A, pharmaceutical compositions comprising these multispecific binding proteins, and therapeutic methods useful for the treatment of cancer. 本文描述了结合NKG2D受体、CD16和CLEC12A的多特异性结合蛋白，包含这些多特异性结合蛋白的药物组合物，以及可用于治疗癌症的治疗方法。