Genetically engineered bacterium for improving yield of cinnamyl amine as well as construction method and application of genetically engineered bacterium

The invention discloses a genetically engineered bacterium for improving the yield of cinnamyl amine as well as a construction method and application of the genetically engineered bacterium, and belongs to the field of fermentation engineering. The purpose of the invention is to increase cinnamyl amine yield from the perspective of biosynthesis. The invention provides a genetically engineered bacterium which is knocked out of a DNA (Deoxyribose Nucleic Acid) binding transcription double regulatory factor arcA and is used for overexpressing a carboxylic acid reductase gene nccar, a phosphopantetheine transferase gene ppase and an omega-transaminase gene oata. The cinnamyl amine yield of the genetically engineered bacterium is 5.5 mM and is increased by 1.5 times compared with that of a strain without arcA knockout, and the method lays a solid foundation for industrial application of cinnamyl amine biosynthesis. 本发明公开一种提高肉桂胺产量的基因工程菌及其构建方法与应用，属于发酵工程领域。为了从生物合成的角度提高肉桂胺产量。本发明提供了一种基因工程菌，其被敲除DNA结合转录双调节因子arcA，并过表达羧酸还原