High-activity sperm optimization method and optimization platform and preparation method thereof

The invention discloses a high-activity sperm optimization method, a high-activity sperm optimization platform and a high-activity sperm preparation method, an acoustic micro-fluidic platform is built by combining an interdigital transducer and a micro-fluidic channel, and surface acoustic waves pro...

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Hauptverfasser: LIN WEIMING, JIANG SHIYAN, WANG JING, DU SHENGRONG, WANG JIARUI, HUANG ZUFANG, SHEN JINGTIAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a high-activity sperm optimization method, a high-activity sperm optimization platform and a high-activity sperm preparation method, an acoustic micro-fluidic platform is built by combining an interdigital transducer and a micro-fluidic channel, and surface acoustic waves provided by the interdigital transducer act on the interior of the micro-fluidic channel; acoustic capturing force provided by two stages of interdigital transducers is utilized to respectively realize capturing and filtering of low-activity sperms and temporary storage of high-activity sperms, and finally, signal input of the second stage of interdigital transducer is closed to realize collection of the high-activity sperms. According to the optimization method, sperms can be captured and stored in a lossless manner, the problems of DNA peroxidation damage, breakage, sperm quality reduction and the like caused by a conventional sperm optimization method are solved, and high-flux, automatic and lossless high-activity