Compound with aggregation-induced emission property as well as preparation method and application thereof

The invention discloses a compound with aggregation-induced emission property as well as a preparation method and application thereof, electron donor and acceptor groups are introduced into a molecular structure, HOMO-LUMO energy levels of molecules are regulated and controlled, and aggregation-indu...

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Hauptverfasser: GOU XUEXIN, CAO HUI, YANG TIANYU, ZHENG ZHENG
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creator GOU XUEXIN
CAO HUI
YANG TIANYU
ZHENG ZHENG
description The invention discloses a compound with aggregation-induced emission property as well as a preparation method and application thereof, electron donor and acceptor groups are introduced into a molecular structure, HOMO-LUMO energy levels of molecules are regulated and controlled, and aggregation-induced emission compounds with different emission colors and high brightness are obtained. The compound has the advantages of large Stokes shift, strong two-photon absorption, good biocompatibility and excellent light stability. Such aggregation-induced emission compounds can specifically image lipid droplets. In addition, the compound can effectively generate active oxygen under an illumination condition, so that the compound can be used for two-photon excited organelle targeted photodynamic therapy. In addition, the compound with the aggregation-induced emission property effectively overcomes the defect of fluorescence quenching caused by aggregation of the traditional fluorescent dye. 本发明公开了具有聚集诱导发光性质的化合物及其制备方法和应用,
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
ADHESIVES
CHEMISTRY
DYES
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
NATURAL RESINS
ORGANIC CHEMISTRY
PAINTS
POLISHES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Compound with aggregation-induced emission property as well as preparation method and application thereof
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