Saliva oral flora biomarkers for diagnosing severe periodontitis and stages thereof

The invention relates to the technical field of biomedicine, and discloses a saliva oral flora biomarker for diagnosing severe periodontitis and stages thereof. The saliva oral cavity flora biomarkers comprise ccSpirochaeta, ooSpirochaetaes, gTrepone, ppSpirochaeta, ffSpirochaetaes and ooBacteroides...

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Hauptverfasser: ZHANG YITAO, ZHANG SHUHAN, REN XIUYUN, YU FEIYAN, CAO CHENGHONG, MI ZHONGQIAN, LI YUN, CHANG MINJING, WANG CAN, QIN DANLEI, AN ZIQIAN, WEI JIAMING, QIAO JUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of biomedicine, and discloses a saliva oral flora biomarker for diagnosing severe periodontitis and stages thereof. The saliva oral cavity flora biomarkers comprise ccSpirochaeta, ooSpirochaetaes, gTrepone, ppSpirochaeta, ffSpirochaetaes and ooBacteroides, and the saliva oral cavity flora biomarkers comprise the following components: ccSpirochaeta, ooSpirochaetaes, gTrepone, ppSpirochaeta, ffSpirochaetaes, ffSpirochaetaes and ooBacteroides. The kit is used for predicting periodontitis illness conditions and auxiliary diagnosis of clinical grading, the detection specificity is good (100%), the sensitivity is high (98%), the kit can indicate conditions of periodontitis tissue microbial flora, and periodontitis clinical diagnosis modes and medication adjustment can be guided so as to reduce the probability of misdiagnosis and missed diagnosis of clinical diagnosis; and the abundance of the biomarker is used as an input index, and the chip technology is utilized, so th