4-1BB agonist as well as preparation method and application thereof

The invention discloses a 4-1BB agonist which is a fusion protein comprising an anti-FAP antibody and 4-1BBL, the anti-FAP antibody is scFv and comprises VL with an amino acid sequence as shown in SEQ ID NO: 1 or the identity of the VL with the SEQ ID NO: 1 being at least 90% and VH with an amino ac...

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Bibliographische Detailangaben
Hauptverfasser:	CHAI HUI, QIAN WENZHENG, LI ZHEN, LI XINRUI, YAN YUNQIU, GU YUCHAO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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