1H-pyrazolo [4, 3-d] pyrimidine compounds as Toll-like receptor 7 (TLR7) agonists
Compounds according to Formula I or II are useful as agonists of Toll-like Receptor 7 (TLR7). (I) (II) Such compounds can be used in the treatment of cancer, in particular in combination with anti-cancer immunotherapeutic agents, or as vaccine adjuvants. 根据式I或II的化合物可用作Toll样受体7(TLR7)的激动剂。(I)(II)此类化合物...
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creator | TUBBY CHRISTINE M POUDEL YVAN GAVAI ASHVINIKUMAR V GANWAR SANJEEV CHOWDARI NAIDU S COX MATTHEW SUBAIAH, MOHAN, ANDAPAN |
description | Compounds according to Formula I or II are useful as agonists of Toll-like Receptor 7 (TLR7). (I) (II) Such compounds can be used in the treatment of cancer, in particular in combination with anti-cancer immunotherapeutic agents, or as vaccine adjuvants.
根据式I或II的化合物可用作Toll样受体7(TLR7)的激动剂。(I)(II)此类化合物能够用于癌症治疗,尤其是与抗癌免疫治疗剂组合,或者用作疫苗佐剂。 |
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根据式I或II的化合物可用作Toll样受体7(TLR7)的激动剂。(I)(II)此类化合物能够用于癌症治疗,尤其是与抗癌免疫治疗剂组合,或者用作疫苗佐剂。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221004&DB=EPODOC&CC=CN&NR=115151548A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221004&DB=EPODOC&CC=CN&NR=115151548A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TUBBY CHRISTINE M</creatorcontrib><creatorcontrib>POUDEL YVAN</creatorcontrib><creatorcontrib>GAVAI ASHVINIKUMAR V</creatorcontrib><creatorcontrib>GANWAR SANJEEV</creatorcontrib><creatorcontrib>CHOWDARI NAIDU S</creatorcontrib><creatorcontrib>COX MATTHEW</creatorcontrib><creatorcontrib>SUBAIAH, MOHAN, ANDAPAN</creatorcontrib><title>1H-pyrazolo [4, 3-d] pyrimidine compounds as Toll-like receptor 7 (TLR7) agonists</title><description>Compounds according to Formula I or II are useful as agonists of Toll-like Receptor 7 (TLR7). (I) (II) Such compounds can be used in the treatment of cancer, in particular in combination with anti-cancer immunotherapeutic agents, or as vaccine adjuvants.
根据式I或II的化合物可用作Toll样受体7(TLR7)的激动剂。(I)(II)此类化合物能够用于癌症治疗,尤其是与抗癌免疫治疗剂组合,或者用作疫苗佐剂。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAg09NAtqCxKrMrPyVeINtFRMNZNiVUAimTmZqZk5qUqJOfnFuSX5qUUKyQWK4Tk5-To5mRmpyoUpSanFpTkFymYK2iE-ASZayokpufnZRaXFPMwsKYl5hSn8kJpbgZFN9cQZw_d1IL8-NTigsTk1LzUknhnP0NDUxA0sXA0JkYNAJ_TNUg</recordid><startdate>20221004</startdate><enddate>20221004</enddate><creator>TUBBY CHRISTINE M</creator><creator>POUDEL YVAN</creator><creator>GAVAI ASHVINIKUMAR V</creator><creator>GANWAR SANJEEV</creator><creator>CHOWDARI NAIDU S</creator><creator>COX MATTHEW</creator><creator>SUBAIAH, MOHAN, ANDAPAN</creator><scope>EVB</scope></search><sort><creationdate>20221004</creationdate><title>1H-pyrazolo [4, 3-d] pyrimidine compounds as Toll-like receptor 7 (TLR7) agonists</title><author>TUBBY CHRISTINE M ; POUDEL YVAN ; GAVAI ASHVINIKUMAR V ; GANWAR SANJEEV ; CHOWDARI NAIDU S ; COX MATTHEW ; SUBAIAH, MOHAN, ANDAPAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115151548A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>TUBBY CHRISTINE M</creatorcontrib><creatorcontrib>POUDEL YVAN</creatorcontrib><creatorcontrib>GAVAI ASHVINIKUMAR V</creatorcontrib><creatorcontrib>GANWAR SANJEEV</creatorcontrib><creatorcontrib>CHOWDARI NAIDU S</creatorcontrib><creatorcontrib>COX MATTHEW</creatorcontrib><creatorcontrib>SUBAIAH, MOHAN, ANDAPAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TUBBY CHRISTINE M</au><au>POUDEL YVAN</au><au>GAVAI ASHVINIKUMAR V</au><au>GANWAR SANJEEV</au><au>CHOWDARI NAIDU S</au><au>COX MATTHEW</au><au>SUBAIAH, MOHAN, ANDAPAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>1H-pyrazolo [4, 3-d] pyrimidine compounds as Toll-like receptor 7 (TLR7) agonists</title><date>2022-10-04</date><risdate>2022</risdate><abstract>Compounds according to Formula I or II are useful as agonists of Toll-like Receptor 7 (TLR7). (I) (II) Such compounds can be used in the treatment of cancer, in particular in combination with anti-cancer immunotherapeutic agents, or as vaccine adjuvants.
根据式I或II的化合物可用作Toll样受体7(TLR7)的激动剂。(I)(II)此类化合物能够用于癌症治疗,尤其是与抗癌免疫治疗剂组合,或者用作疫苗佐剂。</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
title | 1H-pyrazolo [4, 3-d] pyrimidine compounds as Toll-like receptor 7 (TLR7) agonists |
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