Ambroxterol liquid preparation and preparation method thereof
The invention discloses an ambroxol liquid preparation and a preparation method thereof, and each milliliter of the liquid preparation comprises 1-3mg of ambroxol hydrochloride, 0.5-1.5 [mu] g of clenbuterol hydrochloride, sorbitol, strawberry essence, glycerin, hydroxyethyl cellulose, sodium benzoa...
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| creator | LIANG ZHEN SU ZHONGHAI LI YUANCUI CHEN JIULONG HUANG HAOXI |
| description | The invention discloses an ambroxol liquid preparation and a preparation method thereof, and each milliliter of the liquid preparation comprises 1-3mg of ambroxol hydrochloride, 0.5-1.5 [mu] g of clenbuterol hydrochloride, sorbitol, strawberry essence, glycerin, hydroxyethyl cellulose, sodium benzoate, tartaric acid and propylene glycol. The prepared product is good in taste, good in compliance and high in safety, is superior to a commercially available preparation, overcomes the problem of impurity increase of ambroxol hydrochloride in the storage process, and is good in stability.
本发明公开了一种氨溴特罗液体制剂及其制备方法，其中，每毫升液体制剂包含盐酸氨溴索1～3mg、盐酸克仑特罗0.5～1.5μg，还包含山梨醇、草莓香精，以及甘油、羟乙纤维素、苯甲酸钠、酒石酸、丙二醇。本发明制备得到的产品口感佳、顺应性好、安全性高，优于市售制剂，同时克服了放置过程中盐酸氨溴索的杂质增长问题，稳定性好。 |
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本发明公开了一种氨溴特罗液体制剂及其制备方法，其中，每毫升液体制剂包含盐酸氨溴索1～3mg、盐酸克仑特罗0.5～1.5μg，还包含山梨醇、草莓香精，以及甘油、羟乙纤维素、苯甲酸钠、酒石酸、丙二醇。本发明制备得到的产品口感佳、顺应性好、安全性高，优于市售制剂，同时克服了放置过程中盐酸氨溴索的杂质增长问题，稳定性好。</description><language>chi ; eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221004&DB=EPODOC&CC=CN&NR=115137695A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221004&DB=EPODOC&CC=CN&NR=115137695A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIANG ZHEN</creatorcontrib><creatorcontrib>SU ZHONGHAI</creatorcontrib><creatorcontrib>LI YUANCUI</creatorcontrib><creatorcontrib>CHEN JIULONG</creatorcontrib><creatorcontrib>HUANG HAOXI</creatorcontrib><title>Ambroxterol liquid preparation and preparation method thereof</title><description>The invention discloses an ambroxol liquid preparation and a preparation method thereof, and each milliliter of the liquid preparation comprises 1-3mg of ambroxol hydrochloride, 0.5-1.5 [mu] g of clenbuterol hydrochloride, sorbitol, strawberry essence, glycerin, hydroxyethyl cellulose, sodium benzoate, tartaric acid and propylene glycol. The prepared product is good in taste, good in compliance and high in safety, is superior to a commercially available preparation, overcomes the problem of impurity increase of ambroxol hydrochloride in the storage process, and is good in stability.
本发明公开了一种氨溴特罗液体制剂及其制备方法，其中，每毫升液体制剂包含盐酸氨溴索1～3mg、盐酸克仑特罗0.5～1.5μg，还包含山梨醇、草莓香精，以及甘油、羟乙纤维素、苯甲酸钠、酒石酸、丙二醇。本发明制备得到的产品口感佳、顺应性好、安全性高，优于市售制剂，同时克服了放置过程中盐酸氨溴索的杂质增长问题，稳定性好。</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB1zE0qyq8oSS3Kz1HIySwszUxRKChKLUgsSizJzM9TSMxD5eemlmTkpyiUZKQWpean8TCwpiXmFKfyQmluBkU31xBnD93Ugvz41OKCxOTUvNSSeGc_Q0NTQ2NzM0tTR2Ni1AAAe6gw8g</recordid><startdate>20221004</startdate><enddate>20221004</enddate><creator>LIANG ZHEN</creator><creator>SU ZHONGHAI</creator><creator>LI YUANCUI</creator><creator>CHEN JIULONG</creator><creator>HUANG HAOXI</creator><scope>EVB</scope></search><sort><creationdate>20221004</creationdate><title>Ambroxterol liquid preparation and preparation method thereof</title><author>LIANG ZHEN ; SU ZHONGHAI ; LI YUANCUI ; CHEN JIULONG ; HUANG HAOXI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115137695A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LIANG ZHEN</creatorcontrib><creatorcontrib>SU ZHONGHAI</creatorcontrib><creatorcontrib>LI YUANCUI</creatorcontrib><creatorcontrib>CHEN JIULONG</creatorcontrib><creatorcontrib>HUANG HAOXI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIANG ZHEN</au><au>SU ZHONGHAI</au><au>LI YUANCUI</au><au>CHEN JIULONG</au><au>HUANG HAOXI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Ambroxterol liquid preparation and preparation method thereof</title><date>2022-10-04</date><risdate>2022</risdate><abstract>The invention discloses an ambroxol liquid preparation and a preparation method thereof, and each milliliter of the liquid preparation comprises 1-3mg of ambroxol hydrochloride, 0.5-1.5 [mu] g of clenbuterol hydrochloride, sorbitol, strawberry essence, glycerin, hydroxyethyl cellulose, sodium benzoate, tartaric acid and propylene glycol. The prepared product is good in taste, good in compliance and high in safety, is superior to a commercially available preparation, overcomes the problem of impurity increase of ambroxol hydrochloride in the storage process, and is good in stability.
本发明公开了一种氨溴特罗液体制剂及其制备方法，其中，每毫升液体制剂包含盐酸氨溴索1～3mg、盐酸克仑特罗0.5～1.5μg，还包含山梨醇、草莓香精，以及甘油、羟乙纤维素、苯甲酸钠、酒石酸、丙二醇。本发明制备得到的产品口感佳、顺应性好、安全性高，优于市售制剂，同时克服了放置过程中盐酸氨溴索的杂质增长问题，稳定性好。</abstract><oa>free_for_read</oa></addata></record> |
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| title | Ambroxterol liquid preparation and preparation method thereof |
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