Rapid water-soluble immunologic adjuvant and preparation method thereof

The invention discloses a rapid water-soluble immunologic adjuvant and a preparation method thereof, and the rapid water-soluble immunologic adjuvant comprises 20 to 21 parts of PBS dry powder, 0.9 to 1.1 parts of polyinosinic-polycytidylic acid, 0.5 to 0.9 part of polylysine, 0.8 to 1.2 parts of le...

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Hauptverfasser: LIU LICHENG, XU XINGLAN, YAN GUOQUAN, HUANG NANNAN, XIAO YING, XU WENJIE, TAN HUALONG, YUAN BAOFENG, LIU LIZHUANG, LI BO, LIU TONG, MIAO JIANGXIAO, YAN GUANGWEI, YAN BINGYU, ZHAO RUIJIN, XUE MENGQI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a rapid water-soluble immunologic adjuvant and a preparation method thereof, and the rapid water-soluble immunologic adjuvant comprises 20 to 21 parts of PBS dry powder, 0.9 to 1.1 parts of polyinosinic-polycytidylic acid, 0.5 to 0.9 part of polylysine, 0.8 to 1.2 parts of lentinan and 1980 to 2020 parts of deionized water. The preparation method of the rapid water-soluble immunologic adjuvant comprises the steps of weighing, dissolving, uniformly mixing, adjusting the pH value and the like. According to the invention, the rapid water-soluble adjuvant and the protein can be used after being directly, rapidly and uniformly mixed, the number of immunological injections is small, the period is short, and the antibody can be rapidly generated through intramuscular injection, so that the dosage of the antigen is reduced, and the workload is reduced. 本发明公开了一种快速水溶性免疫佐剂及其制备方法,该快速水溶性免疫佐剂,包括20-21份PBS干粉、0.9-1.1份聚肌胞、0.5-0.9份多聚赖氨酸、0.8-1.2份香菇多糖和1980-2020份去离子水;该快速水溶性免疫佐剂的制备方法,包括称量、溶解和混匀并调整pH值等步骤。本发明中