Triterpene derivative and medicinal composition

The invention is composed of a hederagenin derivative of the following formula or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising of this compound as an active ingredient. (wherein R represents OR or NR R . R and R may be the same or different and each represe...

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Hauptverfasser: OHGI TADAAKI, KANDORI KAZUHISA, YOSHIFUSA HIROTO
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creator OHGI TADAAKI
KANDORI KAZUHISA
YOSHIFUSA HIROTO
description The invention is composed of a hederagenin derivative of the following formula or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising of this compound as an active ingredient. (wherein R represents OR or NR R . R and R may be the same or different and each represents hydrogen, alkyl that may be substituted, cycloalkyl that may be substituted, alkenyl that may be substituted, alkinyl that may be substituted, aryl that may be substituted, or a heteroaromatic group that may be substituted, R and R may be the same or different and each represents hydrogen, alkyl that may be substituted, cycloalkyl that may be substituted, alkenyl that may be substituted, alkinyl that may be substituted, acyl that may be subsituted, monoalkylcarbamoyl that may be substituted, dialkylcarbamoyl that may be substituted, or alkoxycarbonyl that may be substituted, or R and R taken together represents carbonyl.) The pharmaceutical composition of the invention is effective for the therapy of nephritis.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
title Triterpene derivative and medicinal composition
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