Triazine compound containing aryl urea structure and application thereof

The invention relates to a triazine compound containing an aryl urea structure as shown in a general formula I and application of the triazine compound, wherein substituent groups R1 and R2 have meanings given in the specification. The invention also relates to a strong effect of inhibiting PI3K and mTOR kinase of the compound shown in the general formula I, and also relates to application of the compound and a pharmaceutical dosage form thereof in preparation of medicines for treating diseases caused by abnormal activation and high expression of PI3K and mTOR kinase, in particular to application in preparation of medicines for treating and/or preventing cancers. 本发明涉及通式Ⅰ所示的含芳基脲结构的三嗪类化合物及其应用其中取代基R1、R2具有在说明书中给出的含义。本发明还涉及通式Ⅰ的化合物具有强的抑制PI3K和mTOR激酶的作用，并且还涉及该类化合物及其药学上的剂型在制备治疗由于PI3K和mTOR激酶异常激活高表达所引起疾病的药物中的用途，特别是在制备治疗和/或预防癌症的药物中的用途。