Pyrimidine heterocyclic compound as well as preparation method and application thereof

The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, prodrugs and solvates thereof, which are useful in the treatment of cancer and inflammation in mammals. The invention also discloses a preparation method of the compound shown in the formula (I) and a pha...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GAO XUGUANG, HUANG GONGCHAO, WANG XINGKAI, TIAN HONGQI, XIA XIANGYING
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator GAO XUGUANG
HUANG GONGCHAO
WANG XINGKAI
TIAN HONGQI
XIA XIANGYING
description The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, prodrugs and solvates thereof, which are useful in the treatment of cancer and inflammation in mammals. The invention also discloses a preparation method of the compound shown in the formula (I) and a pharmaceutical composition containing the compound. 本发明涉及式(I)的化合物或其药物学上可接受的盐、前药和溶剂化物,这类化合物可用于治疗哺乳动物中癌症和炎症。本发明还公开了式(I)化合物的制备方法以及包含所述化合物的药物组合物。
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN115073426A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN115073426A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN115073426A3</originalsourceid><addsrcrecordid>eNrjZAgLqCzKzM1MycxLVchILUktyk-uTM7JTFZIzs8tyC_NS1FILFYoT83JAdEFRakFiUWJJZn5eQq5qSUZ-UBZkIqCAqAOiHBJRmpRan4aDwNrWmJOcSovlOZmUHRzDXH20E0tyI9PLS5ITE7NSy2Jd_YzNDQ1MDc2MTJzNCZGDQB2PToq</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Pyrimidine heterocyclic compound as well as preparation method and application thereof</title><source>esp@cenet</source><creator>GAO XUGUANG ; HUANG GONGCHAO ; WANG XINGKAI ; TIAN HONGQI ; XIA XIANGYING</creator><creatorcontrib>GAO XUGUANG ; HUANG GONGCHAO ; WANG XINGKAI ; TIAN HONGQI ; XIA XIANGYING</creatorcontrib><description>The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, prodrugs and solvates thereof, which are useful in the treatment of cancer and inflammation in mammals. The invention also discloses a preparation method of the compound shown in the formula (I) and a pharmaceutical composition containing the compound. 本发明涉及式(I)的化合物或其药物学上可接受的盐、前药和溶剂化物,这类化合物可用于治疗哺乳动物中癌症和炎症。本发明还公开了式(I)化合物的制备方法以及包含所述化合物的药物组合物。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220920&amp;DB=EPODOC&amp;CC=CN&amp;NR=115073426A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25566,76549</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220920&amp;DB=EPODOC&amp;CC=CN&amp;NR=115073426A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GAO XUGUANG</creatorcontrib><creatorcontrib>HUANG GONGCHAO</creatorcontrib><creatorcontrib>WANG XINGKAI</creatorcontrib><creatorcontrib>TIAN HONGQI</creatorcontrib><creatorcontrib>XIA XIANGYING</creatorcontrib><title>Pyrimidine heterocyclic compound as well as preparation method and application thereof</title><description>The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, prodrugs and solvates thereof, which are useful in the treatment of cancer and inflammation in mammals. The invention also discloses a preparation method of the compound shown in the formula (I) and a pharmaceutical composition containing the compound. 本发明涉及式(I)的化合物或其药物学上可接受的盐、前药和溶剂化物,这类化合物可用于治疗哺乳动物中癌症和炎症。本发明还公开了式(I)化合物的制备方法以及包含所述化合物的药物组合物。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAgLqCzKzM1MycxLVchILUktyk-uTM7JTFZIzs8tyC_NS1FILFYoT83JAdEFRakFiUWJJZn5eQq5qSUZ-UBZkIqCAqAOiHBJRmpRan4aDwNrWmJOcSovlOZmUHRzDXH20E0tyI9PLS5ITE7NSy2Jd_YzNDQ1MDc2MTJzNCZGDQB2PToq</recordid><startdate>20220920</startdate><enddate>20220920</enddate><creator>GAO XUGUANG</creator><creator>HUANG GONGCHAO</creator><creator>WANG XINGKAI</creator><creator>TIAN HONGQI</creator><creator>XIA XIANGYING</creator><scope>EVB</scope></search><sort><creationdate>20220920</creationdate><title>Pyrimidine heterocyclic compound as well as preparation method and application thereof</title><author>GAO XUGUANG ; HUANG GONGCHAO ; WANG XINGKAI ; TIAN HONGQI ; XIA XIANGYING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115073426A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GAO XUGUANG</creatorcontrib><creatorcontrib>HUANG GONGCHAO</creatorcontrib><creatorcontrib>WANG XINGKAI</creatorcontrib><creatorcontrib>TIAN HONGQI</creatorcontrib><creatorcontrib>XIA XIANGYING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GAO XUGUANG</au><au>HUANG GONGCHAO</au><au>WANG XINGKAI</au><au>TIAN HONGQI</au><au>XIA XIANGYING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pyrimidine heterocyclic compound as well as preparation method and application thereof</title><date>2022-09-20</date><risdate>2022</risdate><abstract>The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, prodrugs and solvates thereof, which are useful in the treatment of cancer and inflammation in mammals. The invention also discloses a preparation method of the compound shown in the formula (I) and a pharmaceutical composition containing the compound. 本发明涉及式(I)的化合物或其药物学上可接受的盐、前药和溶剂化物,这类化合物可用于治疗哺乳动物中癌症和炎症。本发明还公开了式(I)化合物的制备方法以及包含所述化合物的药物组合物。</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language chi ; eng
recordid cdi_epo_espacenet_CN115073426A
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Pyrimidine heterocyclic compound as well as preparation method and application thereof
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-17T16%3A19%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GAO%20XUGUANG&rft.date=2022-09-20&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN115073426A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true