Degradable ureteral stent and preparation method thereof

The invention provides a degradable ureteral stent and a preparation method thereof.The preparation method includes the steps that a glycolide monomer and an epsilon-caprolactone monomer serve as raw materials and are subjected to a polymerization reaction to obtain a prepolymer A, and then 1, 10-de...

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1. Verfasser: LAN ZHIYUAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a degradable ureteral stent and a preparation method thereof.The preparation method includes the steps that a glycolide monomer and an epsilon-caprolactone monomer serve as raw materials and are subjected to a polymerization reaction to obtain a prepolymer A, and then 1, 10-decanediol and citric acid serve as raw materials and are subjected to a polymerization reaction to obtain a prepolymer B; then mixing the prepolymer A and the prepolymer B, and carrying out cross-linking polymerization to obtain polyester; then taking polyester and dimethyl pyridine amine as raw materials to obtain modified polyester; and finally, mixing the modified polyester with the nanoparticles to prepare a water-in-oil emulsion, and carrying out extrusion type 3D printing. The degradation time of the ureteral stent is controllable, and the ureteral stent has a shape memory function and a good clinical application prospect. 本发明提供了一种可降解输尿管支架及其制备方法,先以乙交酯单体和ε-己内酯单体为原料,聚合反应得到预聚体A,再以1,10-癸二醇与柠檬酸为原料,聚合反应得到预聚体B;然后将预聚体