3-mercaptoacetylamino-1,5-subsd.2-oxo-axepon derivatives useful as inhibitor of metrix metalloproteinaes
本发明涉及用作基质金属蛋白酶抑制剂的新的3-巯基乙酰氨基-1.5-二取代的-2-氧代-氮杂环庚烷(azepan)衍生物。本发明还要求保护含有所述化合物的药物组合物以及治疗与基质金属蛋白酶抑制作用相关的各种疾病的方法。 The present invention relates to certain novel 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase. Pharmaceutical compositions con...
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creator | M.V. PATEL A.M. WARSHAWSKY G.A. FLYNN |
description | 本发明涉及用作基质金属蛋白酶抑制剂的新的3-巯基乙酰氨基-1.5-二取代的-2-氧代-氮杂环庚烷(azepan)衍生物。本发明还要求保护含有所述化合物的药物组合物以及治疗与基质金属蛋白酶抑制作用相关的各种疾病的方法。
The present invention relates to certain novel 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase. Pharmaceutical compositions containing said compounds as well as methods of treating various disease states responding to inhibition of matrix metalloproteinase are also claimed herein. |
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The present invention relates to certain novel 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase. Pharmaceutical compositions containing said compounds as well as methods of treating various disease states responding to inhibition of matrix metalloproteinase are also claimed herein.</description><edition>7</edition><language>chi ; eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040519&DB=EPODOC&CC=CN&NR=1150205C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040519&DB=EPODOC&CC=CN&NR=1150205C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>M.V. PATEL</creatorcontrib><creatorcontrib>A.M. WARSHAWSKY</creatorcontrib><creatorcontrib>G.A. FLYNN</creatorcontrib><title>3-mercaptoacetylamino-1,5-subsd.2-oxo-axepon derivatives useful as inhibitor of metrix metalloproteinaes</title><description>本发明涉及用作基质金属蛋白酶抑制剂的新的3-巯基乙酰氨基-1.5-二取代的-2-氧代-氮杂环庚烷(azepan)衍生物。本发明还要求保护含有所述化合物的药物组合物以及治疗与基质金属蛋白酶抑制作用相关的各种疾病的方法。
The present invention relates to certain novel 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase. Pharmaceutical compositions containing said compounds as well as methods of treating various disease states responding to inhibition of matrix metalloproteinase are also claimed herein.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjUsOgjAQQNm4MOodegBr-IQTNBhXrtyTAYYwSek0nYHg7cXEA7h6m5f3jtlU2RlTD1EZetS3h5kC2-JaW1k6GW6l5Y0tbBg5mAETraC0ophFcFy8ATEUJupIORkezYyaaPsCvOeYWJECoJyzwwhe8PLjKTP35uUedg-3KHG_B9TWPYuizsu8dq76Q_kAfG5AOA</recordid><startdate>20040519</startdate><enddate>20040519</enddate><creator>M.V. PATEL</creator><creator>A.M. WARSHAWSKY</creator><creator>G.A. FLYNN</creator><scope>EVB</scope></search><sort><creationdate>20040519</creationdate><title>3-mercaptoacetylamino-1,5-subsd.2-oxo-axepon derivatives useful as inhibitor of metrix metalloproteinaes</title><author>M.V. PATEL ; A.M. WARSHAWSKY ; G.A. FLYNN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN1150205CC3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2004</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>M.V. PATEL</creatorcontrib><creatorcontrib>A.M. WARSHAWSKY</creatorcontrib><creatorcontrib>G.A. FLYNN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>M.V. PATEL</au><au>A.M. WARSHAWSKY</au><au>G.A. FLYNN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>3-mercaptoacetylamino-1,5-subsd.2-oxo-axepon derivatives useful as inhibitor of metrix metalloproteinaes</title><date>2004-05-19</date><risdate>2004</risdate><abstract>本发明涉及用作基质金属蛋白酶抑制剂的新的3-巯基乙酰氨基-1.5-二取代的-2-氧代-氮杂环庚烷(azepan)衍生物。本发明还要求保护含有所述化合物的药物组合物以及治疗与基质金属蛋白酶抑制作用相关的各种疾病的方法。
The present invention relates to certain novel 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase. Pharmaceutical compositions containing said compounds as well as methods of treating various disease states responding to inhibition of matrix metalloproteinase are also claimed herein.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | 3-mercaptoacetylamino-1,5-subsd.2-oxo-axepon derivatives useful as inhibitor of metrix metalloproteinaes |
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