Kit for quantitative determination of tacrolimus in whole blood by low steric latex enhanced competitive immunoassay
The invention discloses a kit for quantitative determination of tacrolimus in whole blood by a low-steric-hindrance latex-enhanced competitive immunoassay, the kit comprises a sensitization latex reagent, and the sensitization latex reagent comprises a latex microsphere-NTA-Ni-Fc receptor-anti-tacro...
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| creator | LIN WEIJING SONG XIAOCHAN TAN LINJUAN |
| description | The invention discloses a kit for quantitative determination of tacrolimus in whole blood by a low-steric-hindrance latex-enhanced competitive immunoassay, the kit comprises a sensitization latex reagent, and the sensitization latex reagent comprises a latex microsphere-NTA-Ni-Fc receptor-anti-tacrolimus monoclonal antibody. The invention also discloses a method for quantitatively determining the concentration of tacrolimus in a sample. The kit for determining the immunosuppressant tacrolimus in the whole blood by using the latex-enhanced competitive immunoassay method has the advantages of simple and convenient detection method, small antibody steric hindrance, high sensitivity and the like.
本发明公开了一种低位阻胶乳增强免疫竞争法定量测定全血中他克莫司的试剂盒，其包括致敏胶乳试剂，所述致敏胶乳试剂包含胶乳微球-NTA-Ni-Fc受体-抗他克莫司单克隆抗体。本发明还公开了一种定量测定样本中他克莫司浓度的方法。本发明提供的利用胶乳增强免疫竞争法测定全血中免疫抑制剂他克莫司的试剂盒，具有检测方法简便、抗体位阻小、灵敏度高等优点。 |
| format | Patent |
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本发明公开了一种低位阻胶乳增强免疫竞争法定量测定全血中他克莫司的试剂盒，其包括致敏胶乳试剂，所述致敏胶乳试剂包含胶乳微球-NTA-Ni-Fc受体-抗他克莫司单克隆抗体。本发明还公开了一种定量测定样本中他克莫司浓度的方法。本发明提供的利用胶乳增强免疫竞争法测定全血中免疫抑制剂他克莫司的试剂盒，具有检测方法简便、抗体位阻小、灵敏度高等优点。</description><language>chi ; eng</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220906&DB=EPODOC&CC=CN&NR=115015547A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220906&DB=EPODOC&CC=CN&NR=115015547A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIN WEIJING</creatorcontrib><creatorcontrib>SONG XIAOCHAN</creatorcontrib><creatorcontrib>TAN LINJUAN</creatorcontrib><title>Kit for quantitative determination of tacrolimus in whole blood by low steric latex enhanced competitive immunoassay</title><description>The invention discloses a kit for quantitative determination of tacrolimus in whole blood by a low-steric-hindrance latex-enhanced competitive immunoassay, the kit comprises a sensitization latex reagent, and the sensitization latex reagent comprises a latex microsphere-NTA-Ni-Fc receptor-anti-tacrolimus monoclonal antibody. The invention also discloses a method for quantitatively determining the concentration of tacrolimus in a sample. The kit for determining the immunosuppressant tacrolimus in the whole blood by using the latex-enhanced competitive immunoassay method has the advantages of simple and convenient detection method, small antibody steric hindrance, high sensitivity and the like.
本发明公开了一种低位阻胶乳增强免疫竞争法定量测定全血中他克莫司的试剂盒，其包括致敏胶乳试剂，所述致敏胶乳试剂包含胶乳微球-NTA-Ni-Fc受体-抗他克莫司单克隆抗体。本发明还公开了一种定量测定样本中他克莫司浓度的方法。本发明提供的利用胶乳增强免疫竞争法测定全血中免疫抑制剂他克莫司的试剂盒，具有检测方法简便、抗体位阻小、灵敏度高等优点。</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjMEKglAQRd20iOofpg8IkpLWIkUQtGov43PEgfdmzDdm_n0GfUCrw4VzzzKxGxs02sNzQDE2NH4R1GTUB5Z5qYA2YOh69RyGCCwwtuoJKq9aQzWB1xHifGAHHo3eQNKiOKrBaehorn6bHMIgijHitE4WDfpImx9XyfZyfhTXHXVaUuzQkZCVxT1Ns32aZcdTfvjH-QD_E0W-</recordid><startdate>20220906</startdate><enddate>20220906</enddate><creator>LIN WEIJING</creator><creator>SONG XIAOCHAN</creator><creator>TAN LINJUAN</creator><scope>EVB</scope></search><sort><creationdate>20220906</creationdate><title>Kit for quantitative determination of tacrolimus in whole blood by low steric latex enhanced competitive immunoassay</title><author>LIN WEIJING ; SONG XIAOCHAN ; TAN LINJUAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115015547A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>LIN WEIJING</creatorcontrib><creatorcontrib>SONG XIAOCHAN</creatorcontrib><creatorcontrib>TAN LINJUAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIN WEIJING</au><au>SONG XIAOCHAN</au><au>TAN LINJUAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Kit for quantitative determination of tacrolimus in whole blood by low steric latex enhanced competitive immunoassay</title><date>2022-09-06</date><risdate>2022</risdate><abstract>The invention discloses a kit for quantitative determination of tacrolimus in whole blood by a low-steric-hindrance latex-enhanced competitive immunoassay, the kit comprises a sensitization latex reagent, and the sensitization latex reagent comprises a latex microsphere-NTA-Ni-Fc receptor-anti-tacrolimus monoclonal antibody. The invention also discloses a method for quantitatively determining the concentration of tacrolimus in a sample. The kit for determining the immunosuppressant tacrolimus in the whole blood by using the latex-enhanced competitive immunoassay method has the advantages of simple and convenient detection method, small antibody steric hindrance, high sensitivity and the like.
本发明公开了一种低位阻胶乳增强免疫竞争法定量测定全血中他克莫司的试剂盒，其包括致敏胶乳试剂，所述致敏胶乳试剂包含胶乳微球-NTA-Ni-Fc受体-抗他克莫司单克隆抗体。本发明还公开了一种定量测定样本中他克莫司浓度的方法。本发明提供的利用胶乳增强免疫竞争法测定全血中免疫抑制剂他克莫司的试剂盒，具有检测方法简便、抗体位阻小、灵敏度高等优点。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING |
| title | Kit for quantitative determination of tacrolimus in whole blood by low steric latex enhanced competitive immunoassay |
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