Sildenafil tablet and preparation method thereof

The invention belongs to the technical field of medicines, and particularly discloses a sildenafil tablet and a preparation method thereof. According to the preparation method of the sildenafil tablet, the sildenafil raw material and part of the hydrophilic diluent are mixed and micronized, the micr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DAI YONGLAN, YANG WENLONG, YAN ZHANGLONG, ZHOU LINGWAN, HUANG WUJUN, KANG ZHIHUA
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention belongs to the technical field of medicines, and particularly discloses a sildenafil tablet and a preparation method thereof. According to the preparation method of the sildenafil tablet, the sildenafil raw material and part of the hydrophilic diluent are mixed and micronized, the micronized composition powder after micronization does not agglomerate, good fluidity is kept, and subsequent processing is facilitated, so that the process time is saved, the overall process consumed time of tablet preparation is shortened, and the production efficiency is improved. The method is suitable for industrial large-scale production. The sildenafil tablet has better dissolution rate, and the dissolution performance of the sildenafil tablet is basically consistent with that of an original ground tablet; through combination of a formula and a process, the prepared sildenafil tablet has the advantage of small content change of total impurities and single impurities. 本发明属于医药技术领域,具体公开了一种西地那非片及其制备方法。该西地那非片的制备方法通过将