Polyaminoacid-based particles for use as active principle vectors, and methods for preparing same
本发明涉及可用于活性成分(AP)给药、特别是通过口服或非肠胃途径给予药物或营养活性成分的输送载体。本发明解决的技术问题是提供了对活性成分惰性、粒度可控、坚固而不昂贵的由聚氨基酸基(纳米)或(微米)颗粒组成的输送载体。根据本发明，颗粒的平均粒度小于200μm，由Leu/Glu型聚氨基酸组成，其中Leu/Glu+Leu≥3％，Mw≥4000D。 Vector particles for the admin. of active agent(s) are based on polyamino acid(s) (PAA) and of average size >200 mu m. Their...
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| creator | S. HUILLE A. LEMERCIER G. SOULA |
| description | 本发明涉及可用于活性成分(AP)给药、特别是通过口服或非肠胃途径给予药物或营养活性成分的输送载体。本发明解决的技术问题是提供了对活性成分惰性、粒度可控、坚固而不昂贵的由聚氨基酸基(纳米)或(微米)颗粒组成的输送载体。根据本发明，颗粒的平均粒度小于200μm，由Leu/Glu型聚氨基酸组成，其中Leu/Glu+Leu≥3％，Mw≥4000D。
Vector particles for the admin. of active agent(s) are based on polyamino acid(s) (PAA) and of average size >200 mu m. Their PAA's comprise ≥ 2 types of recurrent amino acids NAA and IAA: NAA = hydrophobic neutral amino acid, and IAA = ionisable lateral chain amino acid; ≥ 1 part of the IAA type recurrent amino acids being in ionised form. The recurrent amino acids of each type may be the same or different and the mol.wt. of the PAA is ≥ 4000 Da (pref. ≥ 5000 Da). |
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Vector particles for the admin. of active agent(s) are based on polyamino acid(s) (PAA) and of average size >200 mu m. Their PAA's comprise ≥ 2 types of recurrent amino acids NAA and IAA: NAA = hydrophobic neutral amino acid, and IAA = ionisable lateral chain amino acid; ≥ 1 part of the IAA type recurrent amino acids being in ionised form. The recurrent amino acids of each type may be the same or different and the mol.wt. of the PAA is ≥ 4000 Da (pref. ≥ 5000 Da).</description><edition>7</edition><language>chi ; eng</language><subject>FOODS OR FOODSTUFFS ; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL ; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS ; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040505&DB=EPODOC&CC=CN&NR=1148170C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040505&DB=EPODOC&CC=CN&NR=1148170C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>S. HUILLE</creatorcontrib><creatorcontrib>A. LEMERCIER</creatorcontrib><creatorcontrib>G. SOULA</creatorcontrib><title>Polyaminoacid-based particles for use as active principle vectors, and methods for preparing same</title><description>本发明涉及可用于活性成分(AP)给药、特别是通过口服或非肠胃途径给予药物或营养活性成分的输送载体。本发明解决的技术问题是提供了对活性成分惰性、粒度可控、坚固而不昂贵的由聚氨基酸基(纳米)或(微米)颗粒组成的输送载体。根据本发明，颗粒的平均粒度小于200μm，由Leu/Glu型聚氨基酸组成，其中Leu/Glu+Leu≥3％，Mw≥4000D。
Vector particles for the admin. of active agent(s) are based on polyamino acid(s) (PAA) and of average size >200 mu m. Their PAA's comprise ≥ 2 types of recurrent amino acids NAA and IAA: NAA = hydrophobic neutral amino acid, and IAA = ionisable lateral chain amino acid; ≥ 1 part of the IAA type recurrent amino acids being in ionised form. The recurrent amino acids of each type may be the same or different and the mol.wt. of the PAA is ≥ 4000 Da (pref. ≥ 5000 Da).</description><subject>FOODS OR FOODSTUFFS</subject><subject>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</subject><subject>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</subject><subject>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjL0KwkAQBtNYiPoO-wAGDAraHxErsbAP690XXbg_bs-Ab6-gD2A1zczMG74k_-IgMbEV195Y4ShzqWI9lMZU6KkgVmJbZQLlItFK9qAJtqaia-LoKKA-kvsGueBzkHgn5YBlMxvZK1Y_Lho69ldzapHTAM1sEVEHc-663aHbb4zZ_qG8AaXkPXA</recordid><startdate>20040505</startdate><enddate>20040505</enddate><creator>S. HUILLE</creator><creator>A. LEMERCIER</creator><creator>G. SOULA</creator><scope>EVB</scope></search><sort><creationdate>20040505</creationdate><title>Polyaminoacid-based particles for use as active principle vectors, and methods for preparing same</title><author>S. HUILLE ; A. LEMERCIER ; G. SOULA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN1148170CC3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2004</creationdate><topic>FOODS OR FOODSTUFFS</topic><topic>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</topic><topic>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</topic><topic>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><toplevel>online_resources</toplevel><creatorcontrib>S. HUILLE</creatorcontrib><creatorcontrib>A. LEMERCIER</creatorcontrib><creatorcontrib>G. SOULA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>S. HUILLE</au><au>A. LEMERCIER</au><au>G. SOULA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Polyaminoacid-based particles for use as active principle vectors, and methods for preparing same</title><date>2004-05-05</date><risdate>2004</risdate><abstract>本发明涉及可用于活性成分(AP)给药、特别是通过口服或非肠胃途径给予药物或营养活性成分的输送载体。本发明解决的技术问题是提供了对活性成分惰性、粒度可控、坚固而不昂贵的由聚氨基酸基(纳米)或(微米)颗粒组成的输送载体。根据本发明，颗粒的平均粒度小于200μm，由Leu/Glu型聚氨基酸组成，其中Leu/Glu+Leu≥3％，Mw≥4000D。
Vector particles for the admin. of active agent(s) are based on polyamino acid(s) (PAA) and of average size >200 mu m. Their PAA's comprise ≥ 2 types of recurrent amino acids NAA and IAA: NAA = hydrophobic neutral amino acid, and IAA = ionisable lateral chain amino acid; ≥ 1 part of the IAA type recurrent amino acids being in ionised form. The recurrent amino acids of each type may be the same or different and the mol.wt. of the PAA is ≥ 4000 Da (pref. ≥ 5000 Da).</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES |
| title | Polyaminoacid-based particles for use as active principle vectors, and methods for preparing same |
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