5 '-cytidine monophosphate monohydrate crystal and preparation method thereof

The molecular formula of the 5 '-cytidine monophosphate monohydrate crystal is C9H16N3O9P, the 5'-cytidine monophosphate monohydrate crystal belongs to a monoclinic system, the space group is P21, the cell parameters a () are 4.858, b () is 8.3267, c () is 17.0704, beta is 90.126 degrees, the cell volume V is 690.5153, and the minimum asymmetric unit number Z in the cell is 2. The invention also provides a preparation method of the crystal. The crystallization method disclosed by the invention is simple and easy to control, and the obtained 5 '-cytidine monophosphate monohydrate crystal is good in flowability, good in stability, uniform in particle size distribution and high in yield, and can be stably stored for a long time. 本发明公开了5'-胞苷单磷酸一水合物晶体，分子式为C9H16N3O9P，属单斜晶系,空间群为P21，晶胞参数a(Å)=4.858，b(Å)=8.3267，c(Å)=17.0704，β=90.126°，晶胞体积V=690.515Å3，晶胞内最小不对称单元数Z=2。本发明还提供了上述晶体的制备方法。本发明的结晶方法简单易控，得到的5'-胞苷酸一水合物晶体流动性好、稳定性好、颗粒尺寸分布均匀、收率高，产品可长期稳定储存。