Method for coating and drying heterologous stem cell-derived extracellular vesicles

Coated and dried extracellular vesicles (EVs) represent an ideal method for preserving and extending the shelf life of the invention, making it available for on-time use and suitable for various species, overcoming the previous problems in isolation and preservation as well as undesirable immune responses. The present invention relates to a coated freeze-dried stem cell-derived EV which can be used at any time to stimulate/accelerate the healing of soft/hard tissue, which can be redissolved in a variety of forms and shapes and stimulated by a laser. The property of the invention is heterologous and/or heterologous EV, which can overcome the difficulty of individual and/or species disease and immune response. 被涂覆和干燥的细胞外囊泡(EV)表示一种用于保存并延长本发明的保质期的理想方法，使其可以按时使用并适用于各种物种，克服了在分离与保存方面的先前难题以及不希望的免疫反应。本发明涉及一种被涂覆的冷冻干燥的干细胞衍生的EV，其可随时用于刺激/加速软/硬组织的愈合，其能够以多种形式和形状复溶，并且通过激光进行刺激。本发明的性质为异源的和/或异种的EV，其能够克服个体和/或物种疾病与免疫反应的难题。