8-alkoxy purine derivative as well as preparation method and application thereof
The invention discloses an 8-alkoxy purine derivative as well as a preparation method and application thereof. The structure of the 8-alkoxy purine derivative is shown as a formula (I). The 8-alkoxy purine derivative provided by the invention is novel in structure and diversified in compound variety...
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| creator | LIAO NENG LIM DONG-EUN LUO ZHE ZHANG YIWEI |
| description | The invention discloses an 8-alkoxy purine derivative as well as a preparation method and application thereof. The structure of the 8-alkoxy purine derivative is shown as a formula (I). The 8-alkoxy purine derivative provided by the invention is novel in structure and diversified in compound variety; the preparation method of the compound does not need a metal catalyst to participate in the reaction, the used catalyst and raw materials are cheap and easy to obtain, the reaction condition is mild, the reaction steps are few, the operation is simple, visible light can be used for catalysis, the selectable range of alcohol reagents is wide, and various required 8-alkoxy purine derivatives can be synthesized; the 8-alkoxy purine derivative can be applied to preparation of antitumor drugs, antiviral drugs or antibacterial drugs.
本发明公开了一种8-烷氧基嘌呤衍生物及其制备方法与应用，该8-烷氧基嘌呤衍生物的结构如式(Ⅰ)所示：本发明提供的8-烷氧基嘌呤衍生物结构新颖，化合物种类多样；该化合物的制备方法无需金属催化剂参与反应，所用催化剂和原料便宜易获得，反应条件温和、反应步骤少、操作简单、可见光即可催化，且醇类试剂可选范围广泛，可合成多种所需的8-烷氧基嘌呤衍生物；该8-烷氧基嘌呤衍生物可应用于制备 |
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本发明公开了一种8-烷氧基嘌呤衍生物及其制备方法与应用，该8-烷氧基嘌呤衍生物的结构如式(Ⅰ)所示：本发明提供的8-烷氧基嘌呤衍生物结构新颖，化合物种类多样；该化合物的制备方法无需金属催化剂参与反应，所用催化剂和原料便宜易获得，反应条件温和、反应步骤少、操作简单、可见光即可催化，且醇类试剂可选范围广泛，可合成多种所需的8-烷氧基嘌呤衍生物；该8-烷氧基嘌呤衍生物可应用于制备</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220524&DB=EPODOC&CC=CN&NR=114524815A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220524&DB=EPODOC&CC=CN&NR=114524815A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIAO NENG</creatorcontrib><creatorcontrib>LIM DONG-EUN</creatorcontrib><creatorcontrib>LUO ZHE</creatorcontrib><creatorcontrib>ZHANG YIWEI</creatorcontrib><title>8-alkoxy purine derivative as well as preparation method and application thereof</title><description>The invention discloses an 8-alkoxy purine derivative as well as a preparation method and application thereof. The structure of the 8-alkoxy purine derivative is shown as a formula (I). The 8-alkoxy purine derivative provided by the invention is novel in structure and diversified in compound variety; the preparation method of the compound does not need a metal catalyst to participate in the reaction, the used catalyst and raw materials are cheap and easy to obtain, the reaction condition is mild, the reaction steps are few, the operation is simple, visible light can be used for catalysis, the selectable range of alcohol reagents is wide, and various required 8-alkoxy purine derivatives can be synthesized; the 8-alkoxy purine derivative can be applied to preparation of antitumor drugs, antiviral drugs or antibacterial drugs.
本发明公开了一种8-烷氧基嘌呤衍生物及其制备方法与应用，该8-烷氧基嘌呤衍生物的结构如式(Ⅰ)所示：本发明提供的8-烷氧基嘌呤衍生物结构新颖，化合物种类多样；该化合物的制备方法无需金属催化剂参与反应，所用催化剂和原料便宜易获得，反应条件温和、反应步骤少、操作简单、可见光即可催化，且醇类试剂可选范围广泛，可合成多种所需的8-烷氧基嘌呤衍生物；该8-烷氧基嘌呤衍生物可应用于制备</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAiw0E3Myc6vqFQoKC3KzEtVSEktyixLLMksS1VILFYoT83JAdEFRakFiUVA4fw8hdzUkoz8FIXEPCAuKMjJTIYIl2SkFqXmp_EwsKYl5hSn8kJpbgZFN9cQZw_d1IL8-NTigsTk1LzUknhnP0NDE1MjEwtDU0djYtQAAJ1fN24</recordid><startdate>20220524</startdate><enddate>20220524</enddate><creator>LIAO NENG</creator><creator>LIM DONG-EUN</creator><creator>LUO ZHE</creator><creator>ZHANG YIWEI</creator><scope>EVB</scope></search><sort><creationdate>20220524</creationdate><title>8-alkoxy purine derivative as well as preparation method and application thereof</title><author>LIAO NENG ; LIM DONG-EUN ; LUO ZHE ; ZHANG YIWEI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN114524815A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LIAO NENG</creatorcontrib><creatorcontrib>LIM DONG-EUN</creatorcontrib><creatorcontrib>LUO ZHE</creatorcontrib><creatorcontrib>ZHANG YIWEI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LIAO NENG</au><au>LIM DONG-EUN</au><au>LUO ZHE</au><au>ZHANG YIWEI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>8-alkoxy purine derivative as well as preparation method and application thereof</title><date>2022-05-24</date><risdate>2022</risdate><abstract>The invention discloses an 8-alkoxy purine derivative as well as a preparation method and application thereof. The structure of the 8-alkoxy purine derivative is shown as a formula (I). The 8-alkoxy purine derivative provided by the invention is novel in structure and diversified in compound variety; the preparation method of the compound does not need a metal catalyst to participate in the reaction, the used catalyst and raw materials are cheap and easy to obtain, the reaction condition is mild, the reaction steps are few, the operation is simple, visible light can be used for catalysis, the selectable range of alcohol reagents is wide, and various required 8-alkoxy purine derivatives can be synthesized; the 8-alkoxy purine derivative can be applied to preparation of antitumor drugs, antiviral drugs or antibacterial drugs.
本发明公开了一种8-烷氧基嘌呤衍生物及其制备方法与应用，该8-烷氧基嘌呤衍生物的结构如式(Ⅰ)所示：本发明提供的8-烷氧基嘌呤衍生物结构新颖，化合物种类多样；该化合物的制备方法无需金属催化剂参与反应，所用催化剂和原料便宜易获得，反应条件温和、反应步骤少、操作简单、可见光即可催化，且醇类试剂可选范围广泛，可合成多种所需的8-烷氧基嘌呤衍生物；该8-烷氧基嘌呤衍生物可应用于制备</abstract><oa>free_for_read</oa></addata></record> |
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| title | 8-alkoxy purine derivative as well as preparation method and application thereof |
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