SiNW chip for biological sample detection and preparation method and application thereof
The invention discloses a SiNW chip for biological sample detection and a preparation method and application thereof, and belongs to the technical field of mass spectrometric detection.The method comprises the following steps that the SiNW chip with a vertical nanowire array is prepared; carrying ou...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a SiNW chip for biological sample detection and a preparation method and application thereof, and belongs to the technical field of mass spectrometric detection.The method comprises the following steps that the SiNW chip with a vertical nanowire array is prepared; carrying out silanization modification on the SiNW chip by utilizing a silanization reagent, so as to obtain the SiNW chip subjected to silanization modification; the SiNW chip subjected to silanization modification can be subjected to gold modification, and the SiNW chip can also be subjected to polydopamine modification before or after gold modification. When the SiNW chip is used for biological sample mass spectrometry, background interference in a detection range can be reduced, the SiNW chip has a certain ultraviolet absorption characteristic, and meanwhile, the sensitivity of sample detection in a positive and negative ion mode and/or a negative ion mode can be improved; and multi-category, high-selectivity and high-cov |
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