Rosemary compound essential oil for inhibiting skin melanoma cell proliferation and application thereof

The invention provides rosemary compound essential oil for inhibiting skin melanoma cell proliferation and application of the rosemary compound essential oil in preparation of drugs for inhibiting skin melanoma cell proliferation. The rosemary compound essential oil for inhibiting skin melanoma cell proliferation provided by the invention is prepared from the following raw materials in parts by mass: 25 to 30 parts of alpha-pinene type rosemary essential oil, 10 to 15 parts of verbenone type rosemary essential oil and 5 to 8 parts of 1, 8-cineole type rosemary essential oil. IC50 of different chemical types of essential oil to melanoma cells B16-F10 is compared, component proportioning of the different chemical types of essential oil is carried out, and finally a compound essential oil formula with the strongest effect of inhibiting B16-F10 proliferation is screened out. The influence of different concentrations of the rosemary compound essential oil on cell cycle change is further explored through experiment