Application of gene Nrgn in product for diagnosing explosive brain injury
The invention relates to the technical field of disease detection, and discloses an application of a gene Nrgn (Neurogranin) in a product for diagnosing explosive brain injury, the expression quantity of the gene Nrgn can be increased 24 hours and 48 hours after the explosive brain injury occurs, an...
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| creator | CAO SHUQIANG CHEN XIAMENG LI MANRUI LIANG WEIBO |
| description | The invention relates to the technical field of disease detection, and discloses an application of a gene Nrgn (Neurogranin) in a product for diagnosing explosive brain injury, the expression quantity of the gene Nrgn can be increased 24 hours and 48 hours after the explosive brain injury occurs, and then the expression quantity of the gene Nrgn is recovered to a pre-injury level. According to the present invention, the expression quantities of the gene Nrgn are increased 24 h and 48 h after the explosive brain injury occurs, and the expression quantities are recovered to the pre-injury level subsequently, such that the gene Nrgn can be adopted as the new marker for the explosive brain injury diagnosis, and the injury time of the explosive brain injury can be identified;
本发明涉及疾病检测技术领域，公开了基因Nrgn(Neurogranin)在诊断爆炸性脑损伤的产品中的应用，所述基因Nrgn在爆炸性脑损伤发生后的24h和48h时的表达量会增高，随后其表达量恢复至伤前水平。本发明发现基因Nrgn在爆炸性脑损伤发生后24h和48h时的表达量均有所增高，且在随后恢复至伤前水平，因此基因Nrgn可作为爆炸性脑损伤诊断用新的标记物，同时还可鉴定爆炸性脑损伤的损伤时间。 |
| format | Patent |
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本发明涉及疾病检测技术领域，公开了基因Nrgn(Neurogranin)在诊断爆炸性脑损伤的产品中的应用，所述基因Nrgn在爆炸性脑损伤发生后的24h和48h时的表达量会增高，随后其表达量恢复至伤前水平。本发明发现基因Nrgn在爆炸性脑损伤发生后24h和48h时的表达量均有所增高，且在随后恢复至伤前水平，因此基因Nrgn可作为爆炸性脑损伤诊断用新的标记物，同时还可鉴定爆炸性脑损伤的损伤时间。</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220329&DB=EPODOC&CC=CN&NR=114250291A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220329&DB=EPODOC&CC=CN&NR=114250291A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CAO SHUQIANG</creatorcontrib><creatorcontrib>CHEN XIAMENG</creatorcontrib><creatorcontrib>LI MANRUI</creatorcontrib><creatorcontrib>LIANG WEIBO</creatorcontrib><title>Application of gene Nrgn in product for diagnosing explosive brain injury</title><description>The invention relates to the technical field of disease detection, and discloses an application of a gene Nrgn (Neurogranin) in a product for diagnosing explosive brain injury, the expression quantity of the gene Nrgn can be increased 24 hours and 48 hours after the explosive brain injury occurs, and then the expression quantity of the gene Nrgn is recovered to a pre-injury level. According to the present invention, the expression quantities of the gene Nrgn are increased 24 h and 48 h after the explosive brain injury occurs, and the expression quantities are recovered to the pre-injury level subsequently, such that the gene Nrgn can be adopted as the new marker for the explosive brain injury diagnosis, and the injury time of the explosive brain injury can be identified;
本发明涉及疾病检测技术领域，公开了基因Nrgn(Neurogranin)在诊断爆炸性脑损伤的产品中的应用，所述基因Nrgn在爆炸性脑损伤发生后的24h和48h时的表达量会增高，随后其表达量恢复至伤前水平。本发明发现基因Nrgn在爆炸性脑损伤发生后24h和48h时的表达量均有所增高，且在随后恢复至伤前水平，因此基因Nrgn可作为爆炸性脑损伤诊断用新的标记物，同时还可鉴定爆炸性脑损伤的损伤时间。</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPB0LCjIyUxOLMnMz1PIT1NIT81LVfArSs9TyMxTKCjKTylNLlFIyy9SSMlMTM_LL87MS1dIrSjIAbLKUhWSihIzQSqzSosqeRhY0xJzilN5oTQ3g6Kba4izh25qQX58anFBYjLQ6JJ4Zz9DQxMjUwMjS0NHY2LUAADZATSt</recordid><startdate>20220329</startdate><enddate>20220329</enddate><creator>CAO SHUQIANG</creator><creator>CHEN XIAMENG</creator><creator>LI MANRUI</creator><creator>LIANG WEIBO</creator><scope>EVB</scope></search><sort><creationdate>20220329</creationdate><title>Application of gene Nrgn in product for diagnosing explosive brain injury</title><author>CAO SHUQIANG ; CHEN XIAMENG ; LI MANRUI ; LIANG WEIBO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN114250291A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>CAO SHUQIANG</creatorcontrib><creatorcontrib>CHEN XIAMENG</creatorcontrib><creatorcontrib>LI MANRUI</creatorcontrib><creatorcontrib>LIANG WEIBO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CAO SHUQIANG</au><au>CHEN XIAMENG</au><au>LI MANRUI</au><au>LIANG WEIBO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Application of gene Nrgn in product for diagnosing explosive brain injury</title><date>2022-03-29</date><risdate>2022</risdate><abstract>The invention relates to the technical field of disease detection, and discloses an application of a gene Nrgn (Neurogranin) in a product for diagnosing explosive brain injury, the expression quantity of the gene Nrgn can be increased 24 hours and 48 hours after the explosive brain injury occurs, and then the expression quantity of the gene Nrgn is recovered to a pre-injury level. According to the present invention, the expression quantities of the gene Nrgn are increased 24 h and 48 h after the explosive brain injury occurs, and the expression quantities are recovered to the pre-injury level subsequently, such that the gene Nrgn can be adopted as the new marker for the explosive brain injury diagnosis, and the injury time of the explosive brain injury can be identified;
本发明涉及疾病检测技术领域，公开了基因Nrgn(Neurogranin)在诊断爆炸性脑损伤的产品中的应用，所述基因Nrgn在爆炸性脑损伤发生后的24h和48h时的表达量会增高，随后其表达量恢复至伤前水平。本发明发现基因Nrgn在爆炸性脑损伤发生后24h和48h时的表达量均有所增高，且在随后恢复至伤前水平，因此基因Nrgn可作为爆炸性脑损伤诊断用新的标记物，同时还可鉴定爆炸性脑损伤的损伤时间。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | Application of gene Nrgn in product for diagnosing explosive brain injury |
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