Manufacture of 1, 3-oxathiolane nucleosides
一种生产1，3-氧硫戊环核苷的方法，包括制备氧硫戊环环，随后将氧硫戊环与嘧啶和嘌呤碱缩合的有效方法。使用此处描述的方法，可以得到单独的对映体化合物。 Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or...
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| Format: | Patent |
| Sprache: | chi ; eng |
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| Zusammenfassung: | 一种生产1，3-氧硫戊环核苷的方法，包括制备氧硫戊环环，随后将氧硫戊环与嘧啶和嘌呤碱缩合的有效方法。使用此处描述的方法，可以得到单独的对映体化合物。
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers. |
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