Water-soluble sarafloxacin hydrochloride granule and preparation method thereof

The invention provides a water-soluble sarafloxacin hydrochloride granule and a preparation method thereof. The invention aims to solve the technical problems that an existing sarafloxacin hydrochloride medicine is poor in treatment effect and serious in medicine residues. The water-soluble sarafloxacin hydrochloride granule is prepared from the following raw materials in parts by weight: 15-45 parts of diethylene diamine, 150-220 parts of a cyclodextrin-methyl vinyl ether/maleic anhydride copolymer, 100 parts of sarafloxacin hydrochloride, 635-735 parts of anhydrous dextrose and a proper amount of water. The preparation method comprises the following steps: respectively weighing the diethylene diamine and the cyclodextrin-methyl vinyl ether/maleic anhydride copolymer, adding the diethylene diamine and the cyclodextrin-methyl vinyl ether/maleic anhydride copolymer into hot water, and carrying out uniform mixing to obtain a mixture I; respectively weighing sarafloxacin hydrochloride and anhydrous dextrose, and